Cochrane · systematic review · CD007922
Positive end‐expiratory pressure (PEEP) during anaesthesia for prevention of mortality and postoperative pulmonary complications
Barbosa, FT, Castro, AA, de Sousa‐Rodrigues, CF · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyPEEP compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation for adult participants given general anaesthesia
Population: adult participants given general anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Postoperative mortality PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation | RR 0.97 | 6 studies · 268 participants | Very low Downgraded: imprecision |
Oxygen efficiency (PaO2/FiO2) day 1 postoperative PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation | no estimate extracted | 2 studies · 80 participants | Very low Downgraded: imprecision |
Oxygen efficiency (PaO2/FiO2) day 3 postoperative PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation | no estimate extracted | 2 studies · 80 participants | Very low Downgraded: imprecision |
Pneumonia PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation | RR 0.4 | 3 studies · 120 participants | Very low Downgraded: imprecision |
Postoperative atelectasis Using a scale from 0‐67 PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation | no estimate extracted | 2 studies · 88 participants | Very low Downgraded: imprecision |
Comparison
Population: All adult patients having general anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Postoperative Mortality | no estimate extracted | 2 studies · 82 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Oxygenation Day 1 postop (PaO2/FiO2) | no estimate extracted | 2 studies · 80 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Oxygenation Day 3 postop (PaO2/FiO2) | no estimate extracted | 2 studies · 80 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Postoperative Atelectasis (Using a scale from: 0‐6) | no estimate extracted | 2 studies · 88 participants | Very low Downgraded: risk of bias, imprecision, indirectness |