Cochrane · systematic review · CD007798

Clinically‐indicated replacement versus routine replacement of peripheral venous catheters

Webster, J, Osborne, S, Rickard, CM, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Vascular4 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 6 · 85.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Effects of clinically‐indicated replacement compared to routine change of peripheral intravenous catheters

Population: any patient requiring a PIVC expected to remain in‐situ for at least 3 days
CD007798.PUB5 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter‐related blood stream infection (during hospitalisation)
Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters
RR 0.61 [0.08, 4.68]7 studies · 7323 participantsLow
Downgraded: inconsistency
Thrombophlebitis (during hospitalisation)
Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters
RR 1.07 [0.93, 1.25]7 studies · 7323 participantsModerate
Downgraded: risk of bias
Thrombophlebitis (per device days) (during hospitalisation)
Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters
RR 0.9 [0.76, 1.08]6 studies · 32709 participantsModerate
Downgraded: risk of bias
All‐cause blood stream infection (during hospitalisation)
Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters
RR 0.47 [0.15, 1.53]1 study · 3283 participantsModerate
Downgraded: inconsistency
Cost (during hospitalisation)
Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters
no estimate extracted3 studies · 4244 participantsModerate
Downgraded: risk of bias
Infiltration (during hospitalisation)
Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters
RR 1.16 [1.06, 1.26]6 studies · 7123 participantsModerate
Downgraded: risk of bias
Catheter blockage (during hospitalisation)
Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters
RR 1.14 [1.01, 1.29]7 studies · 7323 participantsModerate
Downgraded: risk of bias

Clinically‐indicated versus routine changes for peripheral venous catheter‐related complications

Population: patients with peripheral venous catheter‐related complications
CD007798.PUB4 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter‐related bloodstream infection Positive blood culture from a peripheral vein; clinical signs of infection; no other apparent source for the bloodstream infection except the intravenous catheter; and colonised intravenous catheter tip cultu...
Clinically‐indicated vs routine changes
RR 0.61 [0.08, 4.68]5 studies · 4806 participantsModerate
Downgraded: risk of bias, inconsistency
Phlebitis Any definition used by the author
Clinically‐indicated vs routine changes
RR 1.14 [0.93, 1.39]5 studies · 4806 participantsHigh
All‐cause bloodstream infection
Clinically‐indicated vs routine changes
RR 0.47 [0.15, 1.53]1 study · 3283 participantsHigh
Cost Estmated. Based on materials and staff costs5,6
Clinically‐indicated vs routine changes
no estimate extracted3 studies · 4244 participantsHigh

Clinically‐indicated versus routine changes for peripheral venous catheter‐related complications

Population: patients with peripheral venous catheter‐related complications
CD007798.PUB3 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter‐related bloodstream infection Positive blood culture from a peripheral vein; clinical signs of infection; no other apparent source for the bloodstream infection except the intravenous catheter; and colonised intravenous catheter tip cultu...
Clinically‐indicated vs routine changes
RR 0.61 [0.08, 4.68]5 studies · 4806 participantsHigh
Phlebitis Any definition used by the author
Clinically‐indicated vs routine changes
RR 1.14 [0.93, 1.39]5 studies · 4806 participantsHigh
All‐cause bloodstream infection
Clinically‐indicated vs routine changes
RR 0.47 [0.15, 1.53]1 study · 3283 participantsHigh
Cost Estmated. Based on materials and staff costs4,5
Clinically‐indicated vs routine changes
no estimate extracted3 studies · 4244 participantsHigh

Routinely replaced peripheral intravenous catheters for preventing phlebitis and other intravenous catheter related complications

Population: patients with peripheral IV therapy
CD007798.PUB2 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter related bacteraemia Recording in patients medical record
OR 0.57 [0.17, 1.94]5 studies · 3408 participantsHigh
Phlebitis
OR 1.24 [0.97, 1.6]6 studies · 3455 participantsHigh
Cost Australian dollars10. Scale from: 30 to 100.
no estimate extracted2 studies · 961 participantsHigh
Phlebitis per1000 device days Direct observation
OR 1.04 [0.81, 1.32]5 studies · 17201 participantsHigh