Cochrane · systematic review · CD007695

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events

Cates, CJ, Lasserson, TJ · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Airways2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 50%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Regular formoterol compared to regular salmeterol for chronic asthma: serious adverse events

Population: patients with asthma
CD007695.PUB3 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality in adults
Regular formoterol vs regular salmeterol
no estimate extracted3 studies · 1116 participantsLow
All‐cause mortality in children
Regular formoterol vs regular salmeterol
no estimate extracted1 study · 156 participantsVery low
All‐cause SAEs in adults
Regular formoterol vs regular salmeterol
OR 0.77 [0.46, 1.28]3 studies · 1116 participantsLow
All‐cause SAEs in children
Regular formoterol vs regular salmeterol
OR 0.95 [0.06, 15.33]1 study · 156 participantsVery low
Asthma‐related SAEs in adults
Regular formoterol vs regular salmeterol
OR 0.86 [0.29, 2.57]3 studies · 1116 participantsLow
Asthma‐related SAEs in children
Regular formoterol vs regular salmeterol
no estimate extracted1 study · 156 participantsVery low

Regular formoterol compared to regular salmeterol for chronic asthma: serious adverse events

Population: patients with asthma
CD007695.PUB2 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
All cause Mortality ‐ Adults
Regular formoterol vs regular salmeterol
no estimate extracted3 studies · 1116 participantsLow
All cause Mortality ‐ Children
Regular formoterol vs regular salmeterol
no estimate extracted1 study · 156 participantsVery low
All cause Serious Adverse Events ‐ Adults
Regular formoterol vs regular salmeterol
OR 0.77 [0.46, 1.28]3 studies · 1116 participantsLow
All cause Serious Adverse Events ‐ Children
Regular formoterol vs regular salmeterol
OR 0.95 [0.06, 15.33]1 study · 156 participantsVery low
Asthma‐related Serious Adverse Events ‐ Adults
Regular formoterol vs regular salmeterol
OR 0.86 [0.29, 2.57]3 studies · 1116 participantsLow
Asthma‐related Serious Adverse Events ‐ Children
Regular formoterol vs regular salmeterol
no estimate extracted1 study · 156 participantsVery low