Cochrane · systematic review · CD007563
High dose rate versus low dose rate intracavity brachytherapy for locally advanced uterine cervix cancer
Liu, R, Wang, X, Tian, J, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Gynaecological, Neuro-oncology and Orphan CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 6 · 54.5%Moderate 5 · 45.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings
Population: women with locally advanced uterine cervix cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
3‐year overall survival rate (37.2/40.2 mo) | RR 0.95 [0.79, 1.15] | 1 study · 206 participants | Low |
5‐year overall survival rate (3 to 6 yr) | RR 0.93 [0.84, 1.04] | 2 studies · 912 participants | Low |
10‐year overall survival rate (5 to 15 yr) | RR 0.79 [0.52, 1.2] | 1 study · 430 participants | Moderate |
5‐year disease specific survival rate (5 to 15 yr) | RR 0.95 [0.84, 1.07] | 2 studies · 562 participants | Moderate |
10‐year disease specific survival rate (5 to 15 yr) | RR 1.02 [0.88, 1.19] | 1 study · 430 participants | Moderate |
3‐year relapse‐free survive rate (37.2/40.2 mo) | RR 1.04 [0.71, 1.52] | 1 study · 206 participants | Low |
5‐year relapse‐free survive rate (66 mo) | RR 0.96 [0.81, 1.14] | 1 study · 132 participants | Low |
3‐year local control rate (37.2/40.2 mo) | RR 0.95 [0.86, 1.05] | 1 study · 206 participants | Low |
5‐year local control rate (3 to 6 yr) | RR 0.95 [0.87, 1.05] | 1 study · 482 participants | Low |
Locaregional recurrence | RR 1.09 [0.83, 1.43] | 4 studies · 976 participants | Moderate |
Distant metastasis | RR 0.99 [0.72, 1.35] | 4 studies · 976 participants | Moderate |