Cochrane · systematic review · CD007512

Techniques of flushing and reperfusion for liver transplantation

Gurusamy, KS, Naik, P, Abu‐Amara, M, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 10 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Mortality

Population: patients with liver transplantation.
5 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality ‐ Initial hepatic artery versus initial portal vein reperfusion
RR 1.02 [0.22, 4.84]2 studies · 119 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Mortality ‐ Retrograde IVC reperfusion versus simultaneous hepatic artery and portal vein reperfusion
no estimate extracted1 study · 131 participantsVery low
Downgraded: inconsistency, publication bias
Patient survival ‐ Initial hepatic artery versus initial portal vein reperfusion
HR 1.03 [0.37, 2.86]1 study · 1 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Patient survival ‐ Simultaneous hepatic artery and portal vein reperfusion versus initial portal vein reperfusion
HR 0.45 [0.16, 1.28]1 study · 1 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Patient survival ‐ Retrograde IVC reperfusion versus simultaneous hepatic artery and portal vein reperfusion
HR 1.43 [0.58, 3.53]1 study · 1 participantsVery low
Downgraded: inconsistency, publication bias

Graft survival

Population: patients with liver transplantation.
5 questions
OutcomeEffectEvidenceStatus / GRADE
Graft survival ‐ Initial hepatic artery versus initial portal vein flush
HR 1.05 [0.8, 1.37]1 study · 1 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Graft survival ‐ Additional blood venting through IVC versus no additional blood venting through IVC
HR 1.15 [0.87, 1.51]1 study · 1 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Graft survival ‐ Initial hepatic artery versus initial portal vein reperfusion
HR 0.54 [0.15, 1.98]2 studies · 2 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Graft survival ‐ Simultaneous hepatic artery and portal vein reperfusion versus initial portal vein reperfusion
HR 01 study · 1 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Graft survival ‐ Retrograde IVC reperfusion versus simultaneous hepatic artery and portal vein reperfusion
HR 0.88 [0.44, 1.74]1 study · 1 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias