Cochrane · systematic review · CD007372

Home versus inpatient induction of labour for improving birth outcomes

Alfirevic, Z, Gyte, GML, Nogueira Pileggi, V, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
14
No studies
7
Included studies
NR
No studies 7 · 33.3%Ungraded 0 · 0%Very low 14 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Home compared to inpatient induction with vaginal PGE for improving birth outcomes

Population: women having induction of labour at term
7 questions
OutcomeEffectEvidenceStatus / GRADE
Spontaneous vaginal birth№ of participants: 1022(2 RCTs)
Home vs inpatient induction with vaginal PGE
RR 0.91 [0.69, 1.21]NRVery low
Downgraded: risk of bias, imprecision, indirectness
Uterine hyperstimulation№ of participants: 821(1 RCT)
Home vs inpatient induction with vaginal PGE
RR 1.19 [0.4, 3.5]NRVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Caesarean birth№ of participants: 1022(2 RCTs)
Home vs inpatient induction with vaginal PGE
RR 1.01 [0.81, 1.28]NRVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Neonatal infection (up to 28 days)№ of participants: 821(1 RCT)
Home vs inpatient induction with vaginal PGE
RR 1.29 [0.59, 2.82]NRVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Admission to NICU№ of participants: 1022(2 RCTs)
Home vs inpatient induction with vaginal PGE
RR 1.2 [0.5, 2.9]NRVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Serious neonatal morbidity or mortality (up to 28 days)№ of participants: (0 RCTs)
Home vs inpatient induction with vaginal PGE
no estimate extractedNRNo studies
Women's experiences (satisfaction with care) (up to 8 weeks)№ of participants: 399(1 RCT)
Home vs inpatient induction with vaginal PGE
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness

Home compared to inpatient induction with controlled release PGE for improving birth outcomes

Population: women having induction of labour at term
7 questions
OutcomeEffectEvidenceStatus / GRADE
Spontaneous vaginal birth№ of participants: 299(1 RCT)
Home vs inpatient induction with controlled release PGE
RR 0.94 [0.77, 1.14]NRVery low
Downgraded: risk of bias
Uterine hyperstimulation№ of participants: 299(1 RCT)
Home vs inpatient induction with controlled release PGE
RR 1.01 [0.51, 1.98]NRVery low
Downgraded: risk of bias
Caesarean birth№ of participants: 299(1 RCT)
Home vs inpatient induction with controlled release PGE
RR 0.95 [0.64, 1.42]NRVery low
Downgraded: risk of bias
Neonatal infection (up to 28 days)№ of participants: (0 RCTs)
Home vs inpatient induction with controlled release PGE
no estimate extractedNRNo studies
Admission to NICU№ of participants: 299(1 RCT)
Home vs inpatient induction with controlled release PGE
RR 1.38 [0.57, 3.34]NRVery low
Downgraded: risk of bias
Serious neonatal morbidity or mortality (up to 28 days)№ of participants: (0 RCTs)
Home vs inpatient induction with controlled release PGE
no estimate extractedNRNo studies
Mothers' experiences (satisfaction with care) (up to 8 weeks) № of participants: (0 RCT)
Home vs inpatient induction with controlled release PGE
no estimate extractedNRNo studies

Home compared to inpatient induction with balloon or Foley catheter for improving birth outcomes

Population: women having induction of labour at term
7 questions
OutcomeEffectEvidenceStatus / GRADE
Spontaneous vaginal birth№ of participants: 48(1 RCT)
Home vs inpatient induction with balloon or Foley catheter
RR 1.04 [0.54, 1.98]NRVery low
Downgraded: risk of bias
Uterine hyperstimulation№ of participants: 48(1 RCT)
Home vs inpatient induction with balloon or Foley catheter
RR 0.45 [0.03, 6.79]NRVery low
Downgraded: risk of bias
Caesarean birth№ of participants: 159(2 RCTs)
Home vs inpatient induction with balloon or Foley catheter
RR 0.64 [0.41, 1.01]NRVery low
Downgraded: risk of bias, imprecision, indirectness
Neonatal infection (up to 28 days)№ of participants: 48(1 RCT)
Home vs inpatient induction with balloon or Foley catheter
no estimate extractedNRNo studies
Admission to NICU№ of participants: 159(2 RCTs)
Home vs inpatient induction with balloon or Foley catheter
RR 0.37 [0.07, 1.86]NRVery low
Downgraded: risk of bias, imprecision, indirectness
Serious neonatal morbidity or mortality (up to 28 days)№ of participants: 48(1 RCT)
Home vs inpatient induction with balloon or Foley catheter
no estimate extractedNRNo studies
Mothers' experiences (satisfaction with care) (up to 8 weeks)№ of participants: (0 RCTs)
Home vs inpatient induction with balloon or Foley catheter
no estimate extractedNRNo studies