evidencegaps
Cochrane · systematic review · CD007289

Prophylactic chemotherapy for hydatidiform mole to prevent gestational trophoblastic neoplasia

Wang, Q, Fu, J, Hu, L, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Gynaecological, Neuro-oncology and Orphan Cancer2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Comparison

Population: women with a molar pregnancy
CD007289.PUB3 (current) · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of GTN (including low‐quality studies)
RR 0.37 [0.24, 0.57]3 studies · 550 participantsLow
Incidence of GTN (excluding low‐quality studies)
RR 0.28 [0.1, 0.73]1 study · 59 participantsLow
Time to GTN diagnosis (days)
MD 28.72 [13.19, 44.24]2 studies · 33 participantsLow
Number of courses of chemotherapy to cure
MD 1.1 [0.52, 1.68]1 study · 14 participantsVery low

Comparison

Population: women with a molar pregnancy
CD007289.PUB2 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of GTN (including low‐quality studies)
RR 0.37 [0.24, 0.57]3 studies · 550 participantsLow
Incidence of GTN (excluding low‐quality studies)
RR 0.28 [0.1, 0.73]1 study · 59 participantsLow
Time to GTN diagnosis (days)
MD 28.72 [13.19, 44.24]2 studies · 33 participantsLow
Number of courses of chemotherapy to cure
MD 1.1 [0.52, 1.68]1 study · 14 participantsVery low