Cochrane · systematic review · CD006837

High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia

Boonmak, P, Boonmak, S, Pattanittum, P · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Anaesthesia2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

High initial concentration versus low initial concentration for inhalational induction of anaesthesia

Population: patients with inhalational induction of anaesthesia
CD006837.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Time to loss of eyelash reflex
High initial concentration vs low initial concentration
no estimate extracted6 studies · 443 participantsLow
Downgraded: risk of bias
Cough
High initial concentration vs low initial concentration
OR 1.23 [0.53, 2.81]8 studies · 589 participantsLow
Downgraded: risk of bias
Laryngospasm
High initial concentration vs low initial concentration
OR 1.59 [0.16, 15.92]7 studies · 588 participantsLow
Downgraded: risk of bias
Breath holding
High initial concentration vs low initial concentration
OR 1.16 [0.47, 2.83]5 studies · 389 participantsLow
Downgraded: risk of bias
Apneoa
High initial concentration vs low initial concentration
RR 3.14 [1.72, 5.7]2 studies · 160 participantsLow
Downgraded: risk of bias
Patient movement
High initial concentration vs low initial concentration
RR 1.14 [0.69, 1.89]5 studies · 445 participantsLow
Downgraded: risk of bias
Bradycardia
High initial concentration vs low initial concentration
OR 0.8 [0.22, 2.88]3 studies · 199 participantsLow
Downgraded: risk of bias

High initial concentration versus low initial concentration for inhalational induction of anaesthesia

Population: Patients undergoing inhalational induction of anaesthesia
CD006837.PUB2 · 8 questions
OutcomeEffectEvidenceStatus / GRADE
Failed gas induction
High initial concentration vs low initial concentration
no estimate extracted2 studies · 180 participantsLow
Cough
High initial concentration vs low initial concentration
no estimate extracted8 studies · 589 participantsLow
Laryngospasm
High initial concentration vs low initial concentration
no estimate extracted6 studies · 488 participantsLow
Breath holding
High initial concentration vs low initial concentration
no estimate extracted5 studies · 389 participantsLow
Apneoa
High initial concentration vs low initial concentration
no estimate extracted2 studies · 47 participantsLow
Patient movement
High initial concentration vs low initial concentration
no estimate extracted4 studies · 380 participantsLow
Bradycardia
High initial concentration vs low initial concentration
no estimate extracted3 studies · 199 participantsLow
Salivation
High initial concentration vs low initial concentration
no estimate extracted6 studies · 487 participantsModerate