Cochrane · systematic review · CD006751

Vitamin A and beta (β)‐carotene supplementation for cystic fibrosis

de Vries, JJV, Chang, AB, Bonifant, CM, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings

Population: children and adults with CF
6 questions
OutcomeEffectEvidenceStatus / GRADE
Vitamin A deficiency disorders
no estimate extractedNRNo studies
Growth and nutritional status:z‐score for height
no estimate extracted1 study · 24 participantsLow
Downgraded: risk of bias, imprecision
Mortality
no estimate extractedNRNo studies
Respiratory outcomes: FEV1 (% predicted):
no estimate extracted1 study · 24 participantsLow
Downgraded: risk of bias, imprecision
Respiratory outcomes: Antibiotic days per patient in past 3 months
no estimate extracted1 study · 24 participantsLow
Downgraded: risk of bias, imprecision
Adverse events
no estimate extracted1 study · 24 participantsLow
Downgraded: risk of bias, imprecision