Cochrane · systematic review · CD006417

School‐based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents

Mason‐Jones, AJ, Sinclair, D, Mathews, C, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 8.3%Very low 2 · 16.7%Low 7 · 58.3%Moderate 2 · 16.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Educational interventions versus no intervention

Population: adolescents
4 questions
OutcomeEffectEvidenceStatus / GRADE
HIV prevalence
Educational interventions vs no intervention
RR 1.03 [0.8, 1.32]3 studies · 14163 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
HSV2 prevalence
Educational interventions vs no intervention
RR 1.04 [0.94, 1.15]3 studies · 17445 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Syphillis prevalence
Educational interventions vs no intervention
RR 0.81 [0.47, 1.39]1 study · 6977 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Pregnant at end of trial
Educational interventions vs no intervention
RR 0.99 [0.85, 1.16]3 studies · 8280 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness

Incentive‐based programmes versus no intervention

Population: adolescents
4 questions
OutcomeEffectEvidenceStatus / GRADE
HIV prevalence
Incentive‐based programmes vs no intervention
RR 1.23 [0.51, 2.96]2 studies · 3805 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
HSV2 prevalence
Incentive‐based programmes vs no intervention
no estimate extracted2 studies · 7229 participantsVery low
Downgraded: risk of bias, inconsistency, indirectness
Syphillis prevalence
Incentive‐based programmes vs no intervention
RR 0.41 [0.05, 3.27]1 study · 1291 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Pregnant at end of trial
Incentive‐based programmes vs no intervention
RR 0.76 [0.58, 0.99]2 studies · 4200 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness

Combined incentive‐based and educational interventions versus no intervention

Population: adolescents
4 questions
OutcomeEffectEvidenceStatus / GRADE
HIV prevalence
Combined incentive‐based and educational interventions vs no intervention
RR 1.53 [0.45, 5.13]1 study · 2506 participantsLow
Downgraded: risk of bias, imprecision, indirectness
HSV2 prevalence
Combined incentive‐based and educational interventions vs no intervention
RR 0.82 [0.68, 0.99]1 study · 5899 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Syphillis prevalence
Combined incentive‐based and educational interventions vs no intervention
no estimate extracted0 studies · 0 participantsUngraded
Pregnant at end of trial
Combined incentive‐based and educational interventions vs no intervention
RR 0.9 [0.67, 1.19]1 study · 2782 participantsLow
Downgraded: risk of bias, imprecision, indirectness