Cochrane · systematic review · CD006390
Non‐steroid anti‐inflammatory drugs for biliary colic
Fraquelli, M, Casazza, G, Conte, D, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 50%Low 2 · 33.3%Moderate 1 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Non‐steroid anti‐inflammatory drugs versus placebo for biliary colic
Population: people with biliary colic
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lack of pain relief Non‐steroid anti‐inflammatory drugs vs placebo | RR 0.27 [0.19, 0.4] | 5 studies · 208 participants | Moderate Downgraded: risk of bias |
Cholelithiasis‐related complications Non‐steroid anti‐inflammatory drugs vs placebo | RR 0.66 [0.38, 1.15] | 3 studies · 140 participants | Very low Downgraded: risk of bias, imprecision |
Non‐steroid anti‐inflammatory drugs versus opioids for biliary colic
Population: people with biliary colic
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lack of pain relief Non‐steroid anti‐inflammatory drugs vs opioids | RR 0.98 [0.47, 2.07] | 4 studies · 459 participants | Very low Downgraded: risk of bias, imprecision |
Cholelithiasis‐related complications Non‐steroid anti‐inflammatory drugs vs opioids | RR 0.88 [0.14, 5.42] | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision |
Non‐steroid anti‐inflammatory drugs versus spasmolytic drugs for biliary colic
Population: people with biliary colic
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lack of pain relief Non‐steroid anti‐inflammatory drugs vs spasmolytic drugs | RR 0.51 [0.37, 0.71] | 4 studies · 190 participants | Low Downgraded: risk of bias, imprecision |
Cholelithiasis‐related complications Non‐steroid anti‐inflammatory drugs vs spasmolytic drugs | RR 0.27 [0.12, 0.57] | 2 studies · 104 participants | Low Downgraded: risk of bias, imprecision |