Cochrane · systematic review · CD006375

Mid‐urethral sling operations for stress urinary incontinence in women

Ford, AA, Rogerson, L, Cody, JD, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Incontinence3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
43
current version
GRADE rated
31
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 12 · 27.9%Very low 3 · 7%Low 9 · 20.9%Moderate 17 · 39.5%High 2 · 4.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Transobturator (TOR) compared to retropubic (RPR) route for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB4 (current) · 12 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (Short term < 1 year)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.98 [0.96, 1]36 studies · 5514 participantsModerate
Downgraded: risk of bias
Subjective cure (medium term, 1 to 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.97 [0.92, 1.03]5 studies · 683 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Subjective cure (long term, > 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.95 [0.87, 1.04]4 studies · 714 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Bladder or urethral perforation
Transobturator (TOR) vs retropubic (RPR) route
RR 0.13 [0.08, 0.2]40 studies · 6372 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Voiding dysfunction (short and medium term, up to 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.53 [0.43, 0.65]37 studies · 6217 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
De novo urgency or urgency incontinence (short term, up to 12 months)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.98 [0.82, 1.17]31 studies · 4923 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Groin pain
Transobturator (TOR) vs retropubic (RPR) route
RR 4.62 [3.09, 6.92]18 studies · 3226 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Suprapubic pain
Transobturator (TOR) vs retropubic (RPR) route
RR 0.29 [0.11, 0.78]4 studies · 1105 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Vaginal tape erosion (short and medium term, up to 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 1.13 [0.78, 1.65]31 studies · 4743 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Repeat incontinence surgery (short term, within 12 months)
Transobturator (TOR) vs retropubic (RPR) route
RR 1.64 [0.85, 3.16]9 studies · 1402 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Repeat incontinence surgery (long term, > 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 8.79 [3.36, 23]4 studies · 695 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Quality of life
Transobturator (TOR) vs retropubic (RPR) route
no estimate extracted11 studies · 11 participantsUngraded

Retropubic bottom‐to‐top approach compared to retropubic top‐to‐bottom approach for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB4 (current) · 10 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (short term, ≤ 1 year)
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 1.1 [1.01, 1.2]3 studies · 492 participantsModerate
Downgraded: risk of bias
Subjective cure (medium term, 1 to 5 years)
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Subjective cure long term: > 5 years
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Bladder or urethral perforation
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.55 [0.31, 0.98]5 studies · 631 participantsModerate
Downgraded: risk of bias, imprecision
Voiding dysfunction
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.4 [0.18, 0.9]5 studies · 631 participantsModerate
Downgraded: risk of bias, imprecision
De novo urgency or urgency incontinence
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.84 [0.52, 1.34]4 studies · 547 participantsLow
Downgraded: risk of bias, imprecision
Vaginal tape erosion
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.27 [0.08, 0.95]4 studies · 569 participantsModerate
Downgraded: risk of bias, imprecision
Repeat incontinence surgery short term
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Repeat incontinence surgery long term
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Quality of life (IIQ scores)
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted1 study · 84 participantsUngraded

Obturator medial‐to‐lateral approach compared to obturator lateral‐to‐medial approach for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB4 (current) · 11 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (short term ≤ 1 year)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1 [0.96, 1.06]6 studies · 759 participantsLow
Downgraded: risk of bias
Subjective cure (medium term, 1 to 5 years)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.06 [0.91, 1.23]2 studies · 235 participantsLow
Downgraded: risk of bias, imprecision
Subjective cure
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted0 studies · 0 participantsUngraded
Bladder or urethral perforation
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.38 [0.07, 1.92]6 studies · 794 participantsModerate
Downgraded: risk of bias, imprecision
Voiding dysfunction (short and medium term, up to 5 years)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.74 [1.06, 2.88]8 studies · 1121 participantsModerate
Downgraded: risk of bias, imprecision
De novo urgency or urgency incontinence (short term, up to 12 months)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.01 [0.46, 2.2]3 studies · 357 participantsLow
Downgraded: risk of bias, imprecision
Groin pain
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.15 [0.75, 1.76]6 studies · 837 participantsVery low
Downgraded: risk of bias, imprecision
Vaginal tape erosion (short and medium term, up to 5 years)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.42 [0.16, 1.09]7 studies · 1087 participantsVery low
Downgraded: risk of bias, imprecision
Repeat incontinence surgery (short term, up to 12 months)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.64 [0.32, 1.3]2 studies · 532 participantsLow
Downgraded: risk of bias, imprecision
Repeat incontinence surgery
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted0 studies · 0 participantsUngraded
Quality of life
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted1 study · 46 participantsVery low
Downgraded: risk of bias, imprecision

Monofilament compared to multifilament tapes for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB4 (current) · 10 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (short term ≤ 1 year)
Monofilament vs multifilament tapes
RR 1.07 [0.98, 1.16]4 studies · 505 participantsModerate
Downgraded: risk of bias
Subjective cure (medium term: 1 to 5 years)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Subjective cure (long term: > 5 years)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Bladder or urethral perforation
Monofilament vs multifilament tapes
RR 0.76 [0.29, 1.99]4 studies · 496 participantsModerate
Downgraded: risk of bias
Voiding dysfunction
Monofilament vs multifilament tapes
RR 2.2 [0.98, 4.92]3 studies · 400 participantsLow
Downgraded: risk of bias, imprecision
De novo urgency or urgency incontinence
Monofilament vs multifilament tapes
RR 1.09 [0.66, 1.82]4 studies · 496 participantsLow
Downgraded: risk of bias, imprecision
Vaginal tape erosion
Monofilament vs multifilament tapes
RR 0.43 [0.16, 1.14]3 studies · 396 participantsHigh
Repeat incontinence surgery (short term ≤ 1 year)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Repeat incontinence surgery (long term > 5 years)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Quality of life scores ICIQ
Monofilament vs multifilament tapes
no estimate extracted1 study · 96 participantsHigh

Transobturator (TOR) compared to retropubic (RPR) route for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB3 · 13 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (Short term < 1 year)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.98 [0.96, 1]36 studies · 5514 participantsModerate
Downgraded: risk of bias
Subjective cure (medium term, 1 to 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.97 [0.92, 1.03]5 studies · 683 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Subjective cure (long term, > 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.95 [0.87, 1.04]4 studies · 714 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Bladder or urethral perforation
Transobturator (TOR) vs retropubic (RPR) route
RR 0.13 [0.08, 0.2]40 studies · 6372 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Voiding dysfunction (short and medium term, up to 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.53 [0.43, 0.65]37 studies · 6217 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
De novo urgency or urgency incontinence (short term, up to 12 months)
Transobturator (TOR) vs retropubic (RPR) route
RR 0.98 [0.82, 1.17]31 studies · 4923 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Groin pain
Transobturator (TOR) vs retropubic (RPR) route
RR 4.62 [3.09, 6.92]18 studies · 3226 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Suprapubic pain
Transobturator (TOR) vs retropubic (RPR) route
RR 0.29 [0.11, 0.78]4 studies · 1105 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Vaginal tape erosion (short and medium term, up to 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 1.13 [0.78, 1.65]31 studies · 4743 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Repeat incontinence surgery (short term, within 12 months)
Transobturator (TOR) vs retropubic (RPR) route
RR 1.64 [0.85, 3.16]9 studies · 1402 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Repeat incontinence surgery (long term, > 5 years)
Transobturator (TOR) vs retropubic (RPR) route
RR 8.79 [3.36, 23]4 studies · 695 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Cost effectiveness of intervention
Transobturator (TOR) vs retropubic (RPR) route
no estimate extracted1 study · 1 participantsUngraded
Quality of life
Transobturator (TOR) vs retropubic (RPR) route
no estimate extracted11 studies · 11 participantsUngraded

Retropubic bottom‐to‐top approach compared to retropubic top‐to‐bottom approach for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB3 · 11 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (short term, ≤ 1 year)
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 1.1 [1.01, 1.2]3 studies · 492 participantsModerate
Downgraded: risk of bias
Subjective cure (medium term, 1 to 5 years)
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Subjective cure long term: > 5 years
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Bladder or urethral perforation
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.55 [0.31, 0.98]5 studies · 631 participantsModerate
Downgraded: risk of bias, imprecision
Voiding dysfunction
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.4 [0.18, 0.9]5 studies · 631 participantsModerate
Downgraded: risk of bias, imprecision
De novo urgency or urgency incontinence
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.84 [0.52, 1.34]4 studies · 547 participantsLow
Downgraded: risk of bias, imprecision
Vaginal tape erosion
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.27 [0.08, 0.95]4 studies · 569 participantsModerate
Downgraded: risk of bias, imprecision
Repeat incontinence surgery short term
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Repeat incontinence surgery long term
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Cost effectiveness of intervention
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted0 studies · 0 participantsUngraded
Quality of life (IIQ scores)
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted1 study · 84 participantsUngraded

Obturator medial‐to‐lateral approach compared to obturator lateral‐to‐medial approach for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB3 · 12 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (short term ≤ 1 year)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1 [0.96, 1.06]6 studies · 759 participantsLow
Downgraded: risk of bias
Subjective cure (medium term, 1 to 5 years)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.06 [0.91, 1.23]2 studies · 235 participantsLow
Downgraded: risk of bias, imprecision
Subjective cure
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted0 studies · 0 participantsUngraded
Bladder or urethral perforation
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.38 [0.07, 1.92]6 studies · 794 participantsModerate
Downgraded: risk of bias, imprecision
Voiding dysfunction (short and medium term, up to 5 years)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.74 [1.06, 2.88]8 studies · 1121 participantsModerate
Downgraded: risk of bias, imprecision
De novo urgency or urgency incontinence (short term, up to 12 months)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.01 [0.46, 2.2]3 studies · 357 participantsLow
Downgraded: risk of bias, imprecision
Groin pain
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.15 [0.75, 1.76]6 studies · 837 participantsVery low
Downgraded: risk of bias, imprecision
Vaginal tape erosion (short and medium term, up to 5 years)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.42 [0.16, 1.09]7 studies · 1087 participantsVery low
Downgraded: risk of bias, imprecision
Repeat incontinence surgery (short term, up to 12 months)
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.64 [0.32, 1.3]2 studies · 532 participantsLow
Downgraded: risk of bias, imprecision
Repeat incontinence surgery
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted0 studies · 0 participantsUngraded
Cost effectiveness of intervention
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted0 studies · 0 participantsUngraded
Quality of life
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted1 study · 46 participantsVery low
Downgraded: risk of bias, imprecision

Monofilament compared to multifilament tapes for stress urinary incontinence in women

Population: women with stress urinary incontinence
CD006375.PUB3 · 11 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure (short term ≤ 1 year)
Monofilament vs multifilament tapes
RR 1.07 [0.98, 1.16]4 studies · 505 participantsModerate
Downgraded: risk of bias
Subjective cure (medium term: 1 to 5 years)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Subjective cure (long term: > 5 years)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Bladder or urethral perforation
Monofilament vs multifilament tapes
RR 0.76 [0.29, 1.99]4 studies · 496 participantsModerate
Downgraded: risk of bias
Voiding dysfunction
Monofilament vs multifilament tapes
RR 2.2 [0.98, 4.92]3 studies · 400 participantsLow
Downgraded: risk of bias, imprecision
De novo urgency or urgency incontinence
Monofilament vs multifilament tapes
RR 1.09 [0.66, 1.82]4 studies · 496 participantsLow
Downgraded: risk of bias, imprecision
Vaginal tape erosion
Monofilament vs multifilament tapes
RR 0.43 [0.16, 1.14]3 studies · 396 participantsHigh
Repeat incontinence surgery (short term ≤ 1 year)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Repeat incontinence surgery (long term > 5 years)
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Cost effectiveness of intervention
Monofilament vs multifilament tapes
no estimate extracted0 studies · 0 participantsUngraded
Quality of life scores ICIQ
Monofilament vs multifilament tapes
no estimate extracted1 study · 96 participantsHigh

Minimally invasive synthetic suburethral sling operation compared to traditional slings for stress urinary incontinence in women

Population: patients with stress urinary incontinence in women
CD006375.PUB2 · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure within 12 months
Minimally invasive synthetic suburethral sling operation vs traditional slings
RR 1.03 [0.94, 1.13]8 studies · 599 participantsModerate
Downgraded: risk of bias
Denovo urgency or urgency incontinence
Minimally invasive synthetic suburethral sling operation vs traditional slings
RR 0.36 [0.16, 0.79]3 studies · 236 participantsModerate
Downgraded: risk of bias
Voiding Dysfunction
Minimally invasive synthetic suburethral sling operation vs traditional slings
RR 0.75 [0.38, 1.48]3 studies · 254 participantsModerate
Downgraded: risk of bias
Peri‐operative complications
Minimally invasive synthetic suburethral sling operation vs traditional slings
RR 1.09 [0.23, 5.21]1 study · 142 participantsLow
Downgraded: risk of bias, imprecision
Bladder or urethral perforation
Minimally invasive synthetic suburethral sling operation vs traditional slings
RR 2.15 [0.75, 6.16]4 studies · 401 participantsModerate
Downgraded: risk of bias

Minimally invasive synthetic suburethral sling operation compared to open colposuspension for stress urinary incontinence in women

Population: patients with stress urinary incontinence in women
CD006375.PUB2 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure within 12 months
Minimally invasive synthetic suburethral sling operation vs open colposuspension
RR 0.96 [0.9, 1.03]6 studies · 729 participantsModerate
Downgraded: risk of bias
Objective cure within 12 months
Minimally invasive synthetic suburethral sling operation vs open colposuspension
RR 1.04 [0.94, 1.14]3 studies · 468 participantsHigh
Denovo urgency or urgency incontinence
Minimally invasive synthetic suburethral sling operation vs open colposuspension
RR 0.69 [0.38, 1.24]4 studies · 360 participantsModerate
Downgraded: risk of bias
Voiding Dysfunction
Minimally invasive synthetic suburethral sling operation vs open colposuspension
RR 0.62 [0.37, 1.03]6 studies · 704 participantsUngraded
Peri‐operative complications
Minimally invasive synthetic suburethral sling operation vs open colposuspension
RR 0.78 [0.61, 1]5 studies · 653 participantsUngraded
Bladder or urethral perforation
Minimally invasive synthetic suburethral sling operation vs open colposuspension
RR 4.24 [1.71, 10.52]6 studies · 753 participantsModerate
Downgraded: risk of bias

Minimally invasive synthetic suburethral sling operation compared to laparoscopic colposuspension for stress urinary incontinence in women

Population: patients with stress urinary incontinence in women
CD006375.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure within 12 months
Minimally invasive synthetic suburethral sling operation vs laparoscopic colposuspension
RR 1.11 [0.99, 1.24]6 studies · 434 participantsModerate
Downgraded: risk of bias
Objective cure within 12 months
Minimally invasive synthetic suburethral sling operation vs laparoscopic colposuspension
RR 1.15 [1.06, 1.24]6 studies · 513 participantsModerate
Downgraded: risk of bias
Objective cure within 12 months ‐ Lap (mesh) vs TVT
Minimally invasive synthetic suburethral sling operation vs laparoscopic colposuspension
RR 1.51 [1.17, 1.95]1 study · 121 participantsUngraded
Denovo urgency or urgency incontinence
Minimally invasive synthetic suburethral sling operation vs laparoscopic colposuspension
RR 0.31 [0.1, 0.99]2 studies · 169 participantsHigh
Voiding Dysfunction
Minimally invasive synthetic suburethral sling operation vs laparoscopic colposuspension
RR 0.74 [0.33, 1.64]5 studies · 435 participantsHigh
Peri‐operative complications ‐ Lap(sutures) vs TVT
Minimally invasive synthetic suburethral sling operation vs laparoscopic colposuspension
RR 0.87 [0.49, 1.54]7 studies · 350 participantsModerate
Downgraded: risk of bias
Bladder or urethral perforation
Minimally invasive synthetic suburethral sling operation vs laparoscopic colposuspension
RR 2.91 [0.96, 8.86]4 studies · 366 participantsHigh

Retropubic bottom‐to‐top approach versus retropubic top‐to‐bottom approach for stress urinary incontinence in women

Population: patients with stress urinary incontinence in women
CD006375.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure within 12 months
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 1.1 [1.01, 1.2]3 studies · 492 participantsModerate
Downgraded: risk of bias
Objective cure within 12 months
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 1.06 [1.01, 1.11]5 studies · 636 participantsUngraded
Denovo urgency or urgency incontinence
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.84 [0.52, 1.34]4 studies · 547 participantsModerate
Downgraded: risk of bias
Voiding dysfunction
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.4 [0.18, 0.9]5 studies · 631 participantsUngraded
Peri‐operative complications
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.98 [0.53, 1.84]4 studies · 507 participantsModerate
Downgraded: imprecision
QoL Specific
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
no estimate extracted1 study · 84 participantsModerate
Downgraded: imprecision
Bladder or urethral perforation
Retropubic bottom‐to‐top approach vs retropubic top‐to‐bottom approach
RR 0.55 [0.31, 0.98]5 studies · 631 participantsModerate
Downgraded: risk of bias

Obturator medial‐to‐lateral approach versus obturator lateral‐to‐medial approach for stress urinary incontinence in women

Population: patients with stress urinary incontinence in women
CD006375.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure within 12 months
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1 [0.86, 1.16]2 studies · 160 participantsLow
Downgraded: risk of bias
Objective cure within 12 months
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.95 [0.86, 1.04]2 studies · 214 participantsLow
Downgraded: risk of bias
Denovo urgency or urgency incontinence
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.19 [0.53, 2.71]3 studies · 260 participantsVery low
Downgraded: risk of bias, imprecision
Voiding dysfunction
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.3 [0.23, 7.51]2 studies · 214 participantsVery low
Downgraded: risk of bias, imprecision
Peri‐operative complications
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 1.3 [0.23, 7.51]2 studies · 214 participantsVery low
Downgraded: risk of bias, imprecision
QoL Specific
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
no estimate extracted1 study · 46 participantsLow
Downgraded: risk of bias
Bladder or urethral perforation
Obturator medial‐to‐lateral approach vs obturator lateral‐to‐medial approach
RR 0.3 [0.03, 2.82]2 studies · 189 participantsVery low
Downgraded: risk of bias, imprecision

Monofilament compared to multifilament minimally invasive synthetic suburethral slings for stress urinary incontinence in women

Population: patients with stress urinary incontinence in women
CD006375.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure within 12 months
Monofilament vs multifilament minimally invasive synthetic suburethral slings
RR 1.08 [0.98, 1.19]3 studies · 409 participantsModerate
Downgraded: risk of bias
Objective cure within 12 months
Monofilament vs multifilament minimally invasive synthetic suburethral slings
RR 1.15 [1.02, 1.3]2 studies · 309 participantsModerate
Downgraded: risk of bias
Denovo urgency or urgency incontinence
Monofilament vs multifilament minimally invasive synthetic suburethral slings
RR 1.17 [0.67, 2.04]3 studies · 400 participantsModerate
Downgraded: risk of bias
Voiding dysfunction
Monofilament vs multifilament minimally invasive synthetic suburethral slings
RR 2.2 [0.98, 4.92]3 studies · 400 participantsModerate
Downgraded: risk of bias
Peri‐operative complications
Monofilament vs multifilament minimally invasive synthetic suburethral slings
RR 1.16 [0.36, 3.69]2 studies · 279 participantsLow
Downgraded: risk of bias, imprecision
QoL Specific
Monofilament vs multifilament minimally invasive synthetic suburethral slings
no estimate extracted0 studies · 4 participantsUngraded
Bladder or urethral perforation
Monofilament vs multifilament minimally invasive synthetic suburethral slings
RR 0.76 [0.29, 1.99]3 studies · 400 participantsUngraded

Transobturator (TOR) compared to retropubic (RPR) route minimally invasive synthetic suburethral slings for stress urinary incontinence in women

Population: patients with stress urinary incontinence in women
CD006375.PUB2 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective cure within 12 months
Transobturator (TOR) vs retropubic (RPR) route minimally invasive synthetic suburethral slings
RR 1 [0.96, 1.05]10 studies · 1381 participantsModerate
Downgraded: risk of bias
Objective cure within 12 months
Transobturator (TOR) vs retropubic (RPR) route minimally invasive synthetic suburethral slings
RR 0.96 [0.93, 0.99]17 studies · 2434 participantsModerate
Downgraded: risk of bias
Denovo urgency or urgency incontinence
Transobturator (TOR) vs retropubic (RPR) route minimally invasive synthetic suburethral slings
RR 1.08 [0.75, 1.56]14 studies · 1685 participantsModerate
Downgraded: risk of bias
Voiding Dysfunction
Transobturator (TOR) vs retropubic (RPR) route minimally invasive synthetic suburethral slings
RR 0.63 [0.44, 0.89]14 studies · 2085 participantsModerate
Downgraded: risk of bias
Peri‐operative complications
Transobturator (TOR) vs retropubic (RPR) route minimally invasive synthetic suburethral slings
RR 1.03 [0.79, 1.33]13 studies · 1802 participantsModerate
Downgraded: risk of bias
Bladder or urethral perforation
Transobturator (TOR) vs retropubic (RPR) route minimally invasive synthetic suburethral slings
RR 0.14 [0.07, 0.26]18 studies · 2674 participantsModerate
Downgraded: risk of bias