Cochrane · systematic review · CD006308
Workplace interventions for treatment of occupational asthma
Henneberger, PK, Patel, JR, de Groene, GJ, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
WorkAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
13
current version
GRADE rated
10
No studies
3
Included studies
NR
No studies 3 · 23.1%Ungraded 0 · 0%Very low 10 · 76.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Removal from exposure compared to continued exposure for treatment of occupational asthma
Population: workers with occupational asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Absence of asthma symptoms; Removal from exposure vs continued exposure | RR 4.8 [1.67, 13.86] | 9 studies · 641 participants | Very low Downgraded: risk of bias |
Improvement of asthma symptoms; Removal from exposure vs continued exposure | RR 2.47 [1.26, 4.84] | 9 studies · 435 participants | Very low Downgraded: risk of bias |
Change in FEV1 % predicted: Removal from exposure vs continued exposure | no estimate extracted | 10 studies · 898 participants | Very low Downgraded: risk of bias |
Change in NSBH: Removal from exposure vs continued exposure | no estimate extracted | 6 studies · 387 participants | Very low Downgraded: risk of bias |
Reduction of exposure compared to continued exposure for treatment of occupational asthma
Population: workers with occupational asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Absence of asthma symptoms; Reduction of exposure vs continued exposure | RR 2.65 [1.24, 5.68] | 7 studies · 334 participants | Very low Downgraded: risk of bias |
Improvement of asthma symptoms Reduction of exposure vs continued exposure | no estimate extracted | NR | No studies |
Change in FEV1 % predicted: Reduction of exposure vs continued exposure | no estimate extracted | 4 studies · 224 participants | Very low Downgraded: risk of bias |
Change in NSBH: Reduction of exposure vs continued exposure | no estimate extracted | NR | No studies |
Removal from exposure compared to reduction of exposure for treatment of occupational asthma
Population: workers with occupational asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Absence of asthma symptoms; Removal from exposure vs reduction of exposure | RR 6.05 [0.86, 42.34] | 6 studies · 359 participants | Very low Downgraded: risk of bias |
Improvement of asthma symptoms; Removal from exposure vs reduction of exposure | RR 1.11 [0.84, 1.47] | 5 studies · 140 participants | Very low Downgraded: risk of bias |
Change in FEV1 % predicted: Removal from exposure vs reduction of exposure | no estimate extracted | 7 studies · 388 participants | Very low Downgraded: risk of bias |
Change in NSBH: Removal from exposure vs reduction of exposure | no estimate extracted | NR | No studies |
Being unemployed; Removal from exposure vs reduction of exposure | RR 14.28 [2.06, 99.16] | 2 studies · 64 participants | Very low Downgraded: risk of bias |