Cochrane · systematic review · CD006112

Respiratory muscle training for cystic fibrosis

Stanford, G, Ryan, H, Solis-Moya, A · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

Cystic Fibrosis and Genetic Disorders2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 5 · 83.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Summary of findings: respiratory muscle training compared with control for cystic fibrosis

Population: adults and children with cystic fibrosis
CD006112.PUB5 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
FEV1 % predicted
Summary of findings: respiratory muscle training vs control
no estimate extracted4 studies · 83 participantsVery low
Downgraded: risk of bias, imprecision
FVC: % predicted
Summary of findings: respiratory muscle training vs control
no estimate extracted3 studies · 72 participantsVery low
Downgraded: risk of bias, imprecision
Exercise capacity: VO2max (mL/kg/min)
Summary of findings: respiratory muscle training vs control
no estimate extracted3 studies · 54 participantsVery low
Downgraded: risk of bias, imprecision
HRQoL: total score
Summary of findings: respiratory muscle training vs control
no estimate extracted3 studies · 69 participantsVery low
Downgraded: risk of bias, imprecision
Respiratory muscle function: maximal inspiratory pressure (PImax)
Summary of findings: respiratory muscle training vs control
no estimate extracted4 studies · 87 participantsVery low
Downgraded: risk of bias, imprecision
Respiratory muscle function: inspiratory capacity
Summary of findings: respiratory muscle training vs control
no estimate extractedNRNo studies

Comparison

Population: adults and children with cystic fibrosis
CD006112.PUB4 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
FEV1: % predicted
no estimate extracted7 studies · 145 participantsVery low
Downgraded: risk of bias, imprecision
FVC: % predicted
no estimate extracted5 studies · 114 participantsVery low
Downgraded: risk of bias, imprecision
Exercise capacity: VO2max (mL/kg/min)
no estimate extracted3 studies · 54 participantsVery low
Downgraded: risk of bias, imprecision
HRQoL: total score
no estimate extracted3 studies · 69 participantsVery low
Downgraded: risk of bias, imprecision
Respiratory muscle function: maximal inspiratory pressure (PImax)
no estimate extracted3 studies · 51 participantsLow
Downgraded: risk of bias, imprecision
Respiratory muscle function: inspiratory capacity
no estimate extractedNRNo studies