Cochrane · systematic review · CD005433
Lactose avoidance for young children with acute diarrhoea
MacGillivray, S, Fahey, T, McGuire, W · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 16.7%Very low 1 · 16.7%Low 3 · 50%Moderate 1 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Lactose‐free versus lactose‐containing milk, milk products, or foodstuffs for young children with acute diarrhoea
Population: Young children with acute diarrhoea
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Duration of diarrhoea (hours) Lactose‐free vs lactose‐containing milk, milk products, or foodstuffs | no estimate extracted | 16 studies · 1467 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Treatment failure Lactose‐free vs lactose‐containing milk, milk products, or foodstuffs | RR 0.52 [0.39, 0.68] | 18 studies · 1470 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Need for hospitalization Lactose‐free vs lactose‐containing milk, milk products, or foodstuffs | RR 0.79 [0.09, 6.65] | 1 study · 83 participants | Very low Downgraded: imprecision, indirectness |
Diluted (by at least 50%) versus undiluted lactose‐containing milk, milk products, or foodstuffs for young children with acute diarrhoea
Population: Young children with acute diarrhoea
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Duration of diarrhoea (hours) Diluted (by at least 50%) vs undiluted lactose‐containing milk, milk products, or foodstuffs | no estimate extracted | 5 studies · 471 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Treatment failure Diluted (by at least 50%) vs undiluted lactose‐containing milk, milk products, or foodstuffs | RR 0.65 [0.45, 0.94] | 9 studies · 687 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Need for hospitalization Diluted (by at least 50%) vs undiluted lactose‐containing milk, milk products, or foodstuffs | no estimate extracted | 0 studies · 0 participants | Ungraded |