Cochrane · systematic review · CD005259
Interventions for preventing venous thromboembolism in adults undergoing knee arthroscopy
Perrotta, C, Chahla, J, Badariotti, G, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 1 · 14.3%Low 1 · 14.3%Moderate 4 · 57.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyLow‐molecular‐weight heparin compared to no prophylaxis for preventing venous thromboembolism in adults undergoing knee arthroscopy
Population: adults undergoing KA
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PE: assessed by CT arteriography ( Low‐molecular‐weight heparin vs no prophylaxis | RR 1.81 [0.49, 6.65] | 3 studies · 1820 participants | Moderate Downgraded: imprecision |
Symptomatic DVT: assessed by presence of symptoms and confirmed by a positive compression ultrasound ( Low‐molecular‐weight heparin vs no prophylaxis | RR 0.61 [0.18, 2.03] | 4 studies · 1848 participants | Low Downgraded: risk of bias, imprecision |
Asymptomatic DVT: Low‐molecular‐weight heparin vs no prophylaxis | RR 0.14 [0.03, 0.61] | 2 studies · 369 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
All‐cause mortality ( Low‐molecular‐weight heparin vs no prophylaxis | no estimate extracted | 5 studies · 1978 participants | Ungraded |
All adverse effects, including allergies at injection site, minor and major bleeding, others ( Low‐molecular‐weight heparin vs no prophylaxis | RR 1.85 [0.95, 3.59] | 5 studies · 1978 participants | Moderate Downgraded: imprecision |
Major bleeding ( Low‐molecular‐weight heparin vs no prophylaxis | RR 0.98 [0.06, 15.72] | 1 study · 1451 participants | Moderate Downgraded: imprecision |
Minor bleeding ( Low‐molecular‐weight heparin vs no prophylaxis | RR 1.79 [0.84, 3.84] | 5 studies · 1978 participants | Moderate Downgraded: imprecision |
Low‐molecular‐weight heparin compared to control (no prophylactic treatment) for preventing venous thromboembolism in adults undergoing knee arthroscopy
Population: preventing VTE in adults undergoing KA
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PE: Low‐molecular‐weight heparin vs control (no prophylactic treatment) | RR 1.81 [0.49, 6.65] | 3 studies · 1820 participants | Moderate Downgraded: imprecision |
Symptomatic DVT: Low‐molecular‐weight heparin vs control (no prophylactic treatment) | RR 0.61 [0.18, 2.03] | 4 studies · 1848 participants | Low Downgraded: risk of bias, imprecision |
Asymptomatic DVT: Low‐molecular‐weight heparin vs control (no prophylactic treatment) | RR 0.14 [0.03, 0.61] | 2 studies · 369 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Mortality ( Low‐molecular‐weight heparin vs control (no prophylactic treatment) | no estimate extracted | 5 studies · 1978 participants | Ungraded |
All adverse events: including injections allergies, minor and major bleeding, others ( Low‐molecular‐weight heparin vs control (no prophylactic treatment) | RR 1.85 [0.95, 3.59] | 5 studies · 1978 participants | Moderate Downgraded: imprecision |
Major bleeding ( Low‐molecular‐weight heparin vs control (no prophylactic treatment) | RR 0.98 [0.06, 15.72] | 1 study · 1451 participants | Moderate Downgraded: imprecision |
Minor bleeding ( Low‐molecular‐weight heparin vs control (no prophylactic treatment) | RR 1.79 [0.84, 3.84] | 5 studies · 1978 participants | Moderate Downgraded: imprecision |