Cochrane · systematic review · CD005200
Laparoscopic versus open total mesorectal excision for rectal cancer
Vennix, S, Pelzers, L, Bouvy, N, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 85.7%High 1 · 14.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Laparoscopic versus open total mesorectal excision for rectal cancer
Population: people with Rectal Cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Disease‐free survival at 5 years Laparoscopic vs open total mesorectal excision | OR 1.02 [0.76, 1.38] | 4 studies · 943 participants | Moderate |
Overall survival at 5 years Laparoscopic vs open total mesorectal excision | OR 1.15 [0.87, 1.52] | 4 studies · 987 participants | Moderate |
Local recurrences Laparoscopic vs open total mesorectal excision | OR 0.89 [0.57, 1.39] | 8 studies · 1538 participants | Moderate |
Lymph nodes retrieved Laparoscopic vs open total mesorectal excision | no estimate extracted | 11 studies · 3682 participants | High |
CRM positivity Laparoscopic vs open total mesorectal excision | OR 0.99 [0.71, 1.4] | 8 studies · 2313 participants | Moderate |
30‐day morbidity (total) Laparoscopic vs open total mesorectal excision | OR 0.94 [0.8, 1.1] | 11 studies · 3397 participants | Moderate |
Hospital stay (days) Laparoscopic vs open total mesorectal excision | no estimate extracted | 11 studies · 3084 participants | Moderate |