Cochrane · systematic review · CD005188

Interventions to increase influenza vaccination rates of those 60 years and older in the community

Thomas, RE, Lorenzetti, DL · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Acute Respiratory Infections3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
29
current version
GRADE rated
29
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 20.7%High 23 · 79.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Increasing community demand compared to no intervention or another intervention for increasing influenza vaccination uptake

Population: people aged 60 years and older living in the community
CD005188.PUB4 (current) · 12 questions
OutcomeEffectEvidenceStatus / GRADE
Client reminder and recall (postcard) compared to no intervention
Increasing community demand vs no intervention or another intervention
no estimate extracted17 studies · 402367 participantsHigh
Client reminder and recall (tailored letter or postcard or phone call) compared to no intervention
Increasing community demand vs no intervention or another intervention
no estimate extracted16 studies · 195964 participantsHigh
Client reminder and recall (letter + leaflet or postcard) compared to letter
Increasing community demand vs no intervention or another intervention
OR 1.11 [1.07, 1.15]3 studies · 64200 participantsHigh
Client reminder and recall (customised letter or phone call) compared to form letter
Increasing community demand vs no intervention or another intervention
no estimate extracted4 studies · 82465 participantsHigh
Client reminder and recall (telephone call from retired teacher plus educational brochure) compared to usual publicity
Increasing community demand vs no intervention or another intervention
OR 3.33 [1.79, 6.22]1 study · 193 participantsHigh
Client reminder and recall (telephone invitation) compared to invitation to patient when "dropped in" to clinic
Increasing community demand vs no intervention or another intervention
OR 2.72 [1.55, 4.76]1 study · 243 participantsModerate
Downgraded: risk of bias
Brochure + lottery for free groceries compared to no intervention
Increasing community demand vs no intervention or another intervention
OR 1.04 [0.62, 1.76]1 study · 291 participantsHigh
Questionnaires to clients about attitudes
Increasing community demand vs no intervention or another intervention
OR 1.13 [1.03, 1.24]1 study · 13809 participantsHigh
Client‐based education (health risk appraisal) compared to no intervention
Increasing community demand vs no intervention or another intervention
no estimate extracted4 studies · 6300 participantsHigh
Client‐based education (nurses or pharmacists educated and nurses vaccinated participants) compared to no intervention
Increasing community demand vs no intervention or another intervention
OR 3.29 [1.91, 5.66]2 studies · 614 participantsHigh
Client‐based education (nurses educated and vaccinated participants) compared to nurses educated participants
Increasing community demand vs no intervention or another intervention
OR 152.95 [9.39, 2490.67]1 study · 485 participantsHigh
Face‐to‐face 3‐minute conversation compared to no intervention
Increasing community demand vs no intervention or another intervention
OR 1.62 [1.11, 2.35]1 study · 529 participantsModerate
Downgraded: risk of bias

Enhancing vaccination access compared to no intervention or another intervention for increasing influenza vaccination uptake

Population: people aged 60 years and older living in the community
CD005188.PUB4 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Group visits of participants to physician and nurse compared to usual care
Enhancing vaccination access vs no intervention or another intervention
OR 27.19 [1.6, 463.25]1 study · 321 participantsModerate
Downgraded: risk of bias
Home visit compared to invitation to attend influenza vaccination clinic
Enhancing vaccination access vs no intervention or another intervention
OR 1.3 [1.05, 1.61]2 studies · 2112 participantsHigh
Home visit with encouragement to receive influenza vaccination compared to home visit with safety intervention
Enhancing vaccination access vs no intervention or another intervention
OR 0.98 [0.64, 1.5]1 study · 350 participantsHigh
Home visit by nurse or group sessions with encouragement to receive influenza vaccination plus care plan developed with physician compared to no intervention
Enhancing vaccination access vs no intervention or another intervention
no estimate extracted2 studies · 2069 participantsHigh
Free influenza vaccine compared to invitation to be vaccinated but patient pays
Enhancing vaccination access vs no intervention or another intervention
OR 2.36 [1.98, 2.82]2 studies · 2251 participantsHigh
Free influenza vaccine compared to no intervention
Enhancing vaccination access vs no intervention or another intervention
no estimate extracted2 studies · 2250 participantsHigh

Provider‐ or system‐based interventions compared to no intervention or another intervention for increasing influenza vaccination uptake

Population: people aged 60 years and older living in the community
CD005188.PUB4 (current) · 11 questions
OutcomeEffectEvidenceStatus / GRADE
Reminder (to physician) compared to no reminder
Provider‐ or system‐based interventions vs no intervention or another intervention
no estimate extracted4 studies · 202264 participantsHigh
Reminder to physician about all participants compared to reminder about half of participants
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 2.47 [1.53, 3.99]1 study · 316 participantsHigh
Reminder (to hospital staff to vaccinate patient) compared to reminder letter to GP on day of discharge
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 1.7 [0.51, 5.7]1 study · 45 participantsHigh
Posters in clinic displaying influenza vaccination rates to encourage doctors to compete plus postcards to participants compared to no intervention
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 2.03 [1.86, 2.22]1 study · 8376 participantsHigh
Posters in clinic displaying influenza vaccination rates to encourage doctors to compete plus postcards to participants compared to posters alone
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 1.06 [0.95, 1.19]1 study · 5753 participantsHigh
Facilitator encouragement of prevention manoeuvres including influenza vaccination compared to no intervention
Provider‐ or system‐based interventions vs no intervention or another intervention
no estimate extracted3 studies · 2183 participantsModerate
Downgraded: risk of bias
Educational reminders, academic detailing, and peer comparisons to physicians compared to mailed educational materials
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 1.13 [0.8, 1.58]1 study · 1400 participantsModerate
Downgraded: risk of bias
Chart review and feedback to physician plus benchmarking to vaccination rates achieved by top 10% of physicians compared to chart review and feedback
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 3.43 [2.37, 4.97]1 study · 1360 participantsModerate
Downgraded: risk of bias
Educational outreach plus feedback to practice teams versus written feedback to practice teams
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 0.77 [0.72, 0.81]1 study · 27580 participantsHigh
Payment to physicians versus no payment
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 2.22 [1.77, 2.77]2 studies · 2815 participantsHigh
Intervention to increase staff influenza vaccination rate versus no intervention
Provider‐ or system‐based interventions vs no intervention or another intervention
OR 1.04 [0.97, 1.12]1 study · 26432 participantsHigh

Summary of effects of interventions to increase influenza vaccination uptake

Population: all ≥ 60, any country
CD005188.PUB3 · 5 questions
OutcomeEffectEvidenceStatus / GRADE
No intervention
no estimate extracted10 studies · 30377 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
"usual care" ‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐ No intervention ‐‐‐‐‐‐‐‐‐‐‐‐‐ Safety intervention
no estimate extracted2 studies · 710 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Patient paid
no estimate extracted2 studies · 1125 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Chart review and feedback
no estimate extracted3 studies · 15017 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Payment per vaccination
no estimate extracted2 studies · 1559 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness

Summary of effects of interventions to increase influenza vaccination rates

Population: all ≥ 60, any country
CD005188.PUB2 · 5 questions
OutcomeEffectEvidenceStatus / GRADE
No intervention
no estimate extracted10 studies · 30377 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
"usual care" ‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐ No intervention ‐‐‐‐‐‐‐‐‐‐‐‐‐ Safety intervention
no estimate extracted2 studies · 710 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Patient paid
no estimate extracted2 studies · 1125 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Chart review and feedback
no estimate extracted3 studies · 15017 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Payment per vaccination
no estimate extracted2 studies · 1559 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness