Cochrane · systematic review · CD004974

Immunostimulants for preventing respiratory tract infection in children

Del‐Rio‐Navarro, BE, Espinosa‐Rosales, FJ, Flenady, V, et al. · Cochrane Database of Systematic Reviews · 2006 · Cochrane Library

Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table

Population: children (age < 18 years) susceptible to acute respiratory tract infections (ARTIs)
4 questions
OutcomeEffectEvidenceStatus / GRADE
Number of ARTIs
no estimate extracted35 studies · 4060 participantsModerate
Percent difference in ARTIs
no estimate extracted35 studies · 4060 participantsModerate
Incidence of gastrointestinal adverse events
no estimate extracted10 studies · 1457 participantsLow
Incidence of skin adverse events
no estimate extracted10 studies · 1469 participantsLow