Cochrane · systematic review · CD004903
Pneumococcal vaccination during pregnancy for preventing infant infection
Chaithongwongwatthana, S, Yamasmit, W, Limpongsanurak, S, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 0 · 0%Low 6 · 85.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pneumococcal vaccine versus control vaccine for preventing infant infection
Population: Pregnant women undergoing vaccination to prevent infant infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Neonatal death due to pneumococcal infection Pneumococcal vaccine vs control vaccine | no estimate extracted | 0 participants | Ungraded |
Neonatal infection ‐ Pneumonia Pneumococcal vaccine vs control vaccine | RR 0.58 [0.18, 1.9] | 1 study · 149 participants | Low Downgraded: imprecision |
Neonatal infection ‐ Meningitis Pneumococcal vaccine vs control vaccine | RR 3.04 [0.13, 73.44] | 1 study · 149 participants | Low Downgraded: imprecision |
Neonatal infection ‐ Otitis media Pneumococcal vaccine vs control vaccine | RR 0.14 [0.01, 2.75] | 1 study · 149 participants | Low Downgraded: imprecision |
Neonatal infection ‐ All infections Pneumococcal vaccine vs control vaccine | RR 0.66 [0.3, 1.46] | 2 studies · 241 participants | Low Downgraded: imprecision |
Pneumococcal colonization ‐ At 2‐3 months of age Pneumococcal vaccine vs control vaccine | RR 1.13 [0.46, 2.78] | 2 studies · 146 participants | Low Downgraded: imprecision |
Pneumococcal colonization ‐ By 6‐7 months of age Pneumococcal vaccine vs control vaccine | RR 0.67 [0.22, 2.08] | 2 studies · 148 participants | Low Downgraded: imprecision |