Cochrane · systematic review · CD004541

Antidepressants for treating depression in adults with end‐stage kidney disease treated with dialysis

Palmer, SC, Natale, P, Ruospo, M, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 75%Low 0 · 0%Moderate 1 · 25%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Antidepressant therapy versus placebo for depression in dialysis patients

Population: dialysis patients with depression
4 questions
OutcomeEffectEvidenceStatus / GRADE
Dizziness or hypotension
Antidepressant therapy vs placebo
no estimate extracted3 studies · 114 participantsVery low
Nausea
Antidepressant therapy vs placebo
no estimate extracted3 studies · 114 participantsModerate
Sexual dysfunction
Antidepressant therapy vs placebo
no estimate extracted2 studies · 101 participantsVery low
All‐cause mortality
Antidepressant therapy vs placebo
no estimate extracted1 study · 50 participantsVery low