evidence/gaps
Cochrane · systematic review · CD004360

Non‐invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma

Lim, WJ, Mohammed Akram, R, Carson, KV, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Non‐invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma

Population: patients with asthma
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality
no estimate extracted2 studies · 86 participantsVery low
Downgraded: risk of bias, imprecision
Endotracheal intubation
RR 4.48 [0.23, 89.13]2 studies · 86 participantsLow
Downgraded: risk of bias, imprecision
Length of hospital stay
no estimate extracted2 studies · 86 participantsVery low
Downgraded: risk of bias, imprecision
Number of hospital admissions
RR 0.28 [0.09, 0.84]1 study · 33 participantsVery low
Downgraded: risk of bias, imprecision
FEV1 (% predicted) Percentage scale from: 1% to 150%.
MD 14.02 [7.73, 20.32]2 studies · 66 participantsLow
Downgraded: risk of bias, imprecision
FVC (% predicted) Percentage scale from: 1% to 150%.
MD 12.27 [4.38, 20.16]2 studies · 66 participantsLow
Downgraded: risk of bias, imprecision
Respiratory rate (breaths per minute). Scale from: 12 to 40.
no estimate extracted3 studies · 146 participantsLow
Downgraded: risk of bias, imprecision