Cochrane · systematic review · CD004344
Treatment for avascular necrosis of bone in people with sickle cell disease
Martí‐Carvajal, AJ, Solà, I, Agreda‐Pérez, LH · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyComparison
Population: patients with avascular necrosis in people with sickle cell disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ( | RR 0.95 [0.56, 1.6] | 1 study · 38 participants | Very low |
Vaso‐occlusive crisis ( | RR 1.14 [0.72, 1.8] | 1 study · 38 participants | Very low |
Acute chest syndrome ( | RR 1.06 [0.44, 2.56] | 1 study · 38 participants | Very low |
Comparison
Population: patients with Avascular necrosis in people with sickle cell disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ( | RR 0.95 [0.56, 1.6] | 1 study · 38 participants | Very low |
Vaso‐occlusive crisis ( | RR 1.14 [0.72, 1.8] | 1 study · 38 participants | Very low |
Acute chest syndrome ( | RR 1.06 [0.44, 2.56] | 1 study · 38 participants | Very low |
Comparison
Population: patients with Avascular necrosis in people with sickle cell disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ( | RR 0.95 [0.56, 1.6] | 1 study · 38 participants | Very low |
Vaso‐occlusive crisis ( | RR 1.14 [0.72, 1.8] | 1 study · 38 participants | Very low |
Acute chest syndrome ( | RR 1.06 [0.44, 2.56] | 1 study · 38 participants | Very low |
Comparison
Population: patients with Avascular necrosis in people with sickle cell disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ( | RR 0.95 [0.56, 1.6] | 1 study · 38 participants | Very low |
Vaso‐occlusive crisis ( | RR 1.14 [0.72, 1.8] | 1 study · 38 participants | Very low |
Acute chest syndrome ( | RR 1.06 [0.44, 2.56] | 1 study · 38 participants | Very low |
Comparison
Population: patients with Avascular necrosis in people with sickle cell disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ( | RR 0.95 [0.56, 1.6] | 1 study · 38 participants | Very low |
Vaso‐occlusive crisis ( | RR 1.14 [0.72, 1.8] | 1 study · 38 participants | Very low |
Acute chest syndrome ( | RR 1.06 [0.44, 2.56] | 1 study · 38 participants | Very low |