Cochrane · systematic review · CD004318
Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery
Felder, S, Rasmussen, MS, King, R, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 10 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyComparison
Population: patients undergoing abdominal or pelvic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All VTE | OR 0.38 [0.26, 0.54] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT | OR 0.39 [0.27, 0.55] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Proximal DVT | OR 0.22 [0.1, 0.47] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Symptomatic VTE | OR 0 [0.08, 1.11] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Bleeding complications | OR 1.1 [0.67, 1.81] | 7 studies · 2239 participants | Moderate Downgraded: risk of bias, imprecision |
Mortality | OR 1.15 [0.72, 1.84] | 7 studies · 1881 participants | Moderate Downgraded: risk of bias, imprecision |
Additional summary of findings
Population: patients undergoing abdominal or pelvic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All VTE (subgroup analysis open only) | OR 0.42 [0.29, 0.6] | 6 studies · 1503 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT (subgroup analysis open only) | OR 0.43 [0.3, 0.62] | 6 studies · 1503 participants | Moderate Downgraded: risk of bias, imprecision |
All VTE (sensitivity analysis unpublished) | OR 0.38 [0.27, 0.56] | 6 studies · 1620 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT (sensitivity analysis unpublished) | OR 0.4 [0.27, 0.58] | 6 studies · 1620 participants | Moderate Downgraded: risk of bias, imprecision |
Comparison
Population: patients undergoing abdominal or pelvic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All VTE | OR 0.38 [0.26, 0.54] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT | OR 0.39 [0.27, 0.55] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Proximal DVT | OR 0.22 [0.1, 0.47] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Symptomatic VTE | OR 0 [0.08, 1.11] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Bleeding complications | OR 1.1 [0.67, 1.81] | 7 studies · 2239 participants | Moderate Downgraded: risk of bias, imprecision |
Mortality | OR 1.15 [0.72, 1.84] | 7 studies · 1881 participants | Moderate Downgraded: risk of bias, imprecision |
Additional summary of findings
Population: patients undergoing abdominal or pelvic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All VTE (subgroup analysis open only) | OR 0.42 [0.29, 0.6] | 6 studies · 1503 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT (subgroup analysis open only) | OR 0.43 [0.3, 0.62] | 6 studies · 1503 participants | Moderate Downgraded: risk of bias, imprecision |
All VTE (sensitivity analysis unpublished) | OR 0.38 [0.27, 0.56] | 6 studies · 1620 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT (sensitivity analysis unpublished) | OR 0.4 [0.27, 0.58] | 6 studies · 1620 participants | Moderate Downgraded: risk of bias, imprecision |
Comparison
Population: patients undergoing abdominal or pelvic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All VTE | OR 0.38 [0.26, 0.54] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT | OR 0.39 [0.27, 0.55] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Proximal DVT | OR 0.22 [0.1, 0.47] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Symptomatic VTE | OR 0 [0.08, 1.11] | 7 studies · 1728 participants | Moderate Downgraded: risk of bias, imprecision |
Bleeding complications | OR 1.1 [0.67, 1.81] | 7 studies · 2239 participants | Moderate Downgraded: risk of bias, imprecision |
Additional summary of findings
Population: patients undergoing abdominal or pelvic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All VTE (subgroup analysis open only) | OR 0.42 [0.29, 0.6] | 6 studies · 1503 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT (subgroup analysis open only) | OR 0.43 [0.3, 0.62] | 6 studies · 1503 participants | Moderate Downgraded: risk of bias, imprecision |
All VTE (sensitivity analysis unpublished) | OR 0.38 [0.27, 0.56] | 6 studies · 1620 participants | Moderate Downgraded: risk of bias, imprecision |
All DVT (sensitivity analysis unpublished) | OR 0.4 [0.27, 0.58] | 6 studies · 1620 participants | Moderate Downgraded: risk of bias, imprecision |