Cochrane · systematic review · CD004312
Botulinum toxin type A versus anticholinergics for cervical dystonia
Rodrigues, FB, Duarte, GS, Castelão, M, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Movement DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 5 · 71.4%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Botulinum toxin type A compared to anticholinergics for cervical dystonia
Population: cervical dystonia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cervical dystonia‐specific improvement Botulinum toxin type A vs anticholinergics | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Adverse events Botulinum toxin type A vs anticholinergics | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Subjective evaluation of clinical status Botulinum toxin type A vs anticholinergics | no estimate extracted | NR | No studies |
Cervical dystonia‐specific pain Botulinum toxin type A vs anticholinergics | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Health‐related quality of life Botulinum toxin type A vs anticholinergics | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Tolerability assessed by dropouts due to adverse events Botulinum toxin type A vs anticholinergics | RR 0.33 [0.04, 3.04] | NR | Very low Downgraded: risk of bias, imprecision |
Duration of effect Botulinum toxin type A vs anticholinergics | no estimate extracted | NR | No studies |