Cochrane · systematic review · CD004135

Transurethral microwave thermotherapy for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia

Franco, JVA, Garegnani, L, Escobar Liquitay, CM, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Urology2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 25%Low 4 · 33.3%Moderate 5 · 41.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Transurethral microwave thermotherapy compared to transurethral resection of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia

Population: men with lower urinary tract symptoms due to benign prostatic hyperplasia
CD004135.PUB4 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Urologic symptom scores
Transurethral microwave thermotherapy vs transurethral resection of the prostate
no estimate extracted4 studies · 306 participantsModerate
Downgraded: risk of bias
Quality of life
Transurethral microwave thermotherapy vs transurethral resection of the prostate
no estimate extracted1 study · 136 participantsModerate
Downgraded: risk of bias
Major adverse events
Transurethral microwave thermotherapy vs transurethral resection of the prostate
RR 0.2 [0.09, 0.43]6 studies · 525 participantsModerate
Downgraded: risk of bias
Retreatment Participants requiring additional procedures or surgery
Transurethral microwave thermotherapy vs transurethral resection of the prostate
RR 7.07 [1.94, 25.82]5 studies · 463 participantsModerate
Downgraded: risk of bias, imprecision
Erectile function (sexually‐active men only)
Transurethral microwave thermotherapy vs transurethral resection of the prostate
RR 0.63 [0.24, 1.63]5 studies · 337 participantsLow
Downgraded: risk of bias, imprecision
Ejaculatory function (sexually‐active men only)
Transurethral microwave thermotherapy vs transurethral resection of the prostate
RR 0.36 [0.24, 0.53]4 studies · 241 participantsLow
Downgraded: risk of bias, imprecision

Transurethral microwave thermotherapy compared to sham treatment for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia

Population: men with lower urinary tract symptoms due to benign prostatic hyperplasia
CD004135.PUB4 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Urologic symptom scores
Transurethral microwave thermotherapy vs sham treatment
no estimate extracted4 studies · 483 participantsModerate
Downgraded: risk of bias
Quality of life
Transurethral microwave thermotherapy vs sham treatment
no estimate extracted2 studies · 347 participantsLow
Downgraded: risk of bias, imprecision
Major adverse events
Transurethral microwave thermotherapy vs sham treatment
no estimate extracted8 studies · 924 participantsVery low
Downgraded: risk of bias, imprecision
Retreatment Participants requiring additional procedures or surgery
Transurethral microwave thermotherapy vs sham treatment
RR 0.27 [0.08, 0.88]2 studies · 82 participantsLow
Downgraded: risk of bias, imprecision
Erectile function (sexually‐active men only)
Transurethral microwave thermotherapy vs sham treatment
no estimate extracted3 studies · 375 participantsVery low
Downgraded: risk of bias, imprecision
Ejaculatory function (sexually‐active men only)
Transurethral microwave thermotherapy vs sham treatment
no estimate extracted5 studies · 727 participantsVery low
Downgraded: risk of bias, imprecision

Comparison

Population: men with symptomatic benign prostatic hyperplasia
CD004135.PUB3 · 3 questions
OutcomeEffectEvidenceStatus / GRADE
International Prostate Symptom Score (IPSS).
no estimate extracted306 participantsModerate
Downgraded: imprecision
Madsen‐Iversen Symptom Score Range 0 to 27 points
no estimate extracted5 studies · 338 participantsModerate
Downgraded: imprecision
Peak Flow Rate (Qmax): Measurement: mL per second
no estimate extracted2 studies · 108 participantsModerate
Downgraded: imprecision