Cochrane · systematic review · CD004121

Non‐steroidal anti‐inflammatory agents to induce regression and prevent the progression of cervical intraepithelial neoplasia

Grabosch, SM, Shariff, OM, Helm, CW · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Gynaecological, Neuro-oncology and Orphan Cancer2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 2 · 66.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Comparison

Population: women with CIN 2 or CIN 3
CD004121.PUB4 (current) · 3 questions
OutcomeEffectEvidenceStatus / GRADE
Progression of CIN to a higher grade of CIN
RR 0.54 [0.06, 5.24]25 participantsVery low
Downgraded: imprecision
Partial or complete regression of CIN 2 or CIN 3
RR 1.45 [0.93, 2.27]132 participantsModerate
Downgraded: imprecision
Complete regression of CIN 2 or CIN 3
RR 1.31 [0.65, 2.67]116 participantsModerate
Downgraded: imprecision

Comparison

Population: women with CIN 2 or CIN 3
CD004121.PUB3 · 3 questions
OutcomeEffectEvidenceStatus / GRADE
Complete regression of CIN 2 or CIN 3
RR 2.17 [0.48, 9.76]25 participantsVery low
Downgraded: imprecision
Partial or complete regression of CIN 2 or CIN 3
RR 2.35 [1.03, 5.35]41 participantsVery low
Downgraded: imprecision
Progression of CIN to a higher grade of CIN
RR 0.54 [0.06, 5.24]25 participantsVery low
Downgraded: imprecision