Cochrane · systematic review · CD003511
Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology
Haas, DM, Hathaway, TJ, Ramsey, PS · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 2 · 66.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyProgestogen compared to placebo/no treatment for preventing miscarriage in women with recurrent miscarriage of unclear etiology
Population: women with recurrent miscarriage of unclear etiology
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Miscarriage (all trials) Progestogen vs placebo/no treatment | RR 0.73 [0.54, 1] | 10 studies · 1684 participants | Moderate Downgraded: risk of bias |
Live birth rate Progestogen vs placebo/no treatment | RR 1.07 [1, 1.13] | 6 studies · 1411 participants | Moderate Downgraded: risk of bias |
Preterm birth Progestogen vs placebo/no treatment | RR 1.13 [0.53, 2.41] | 4 studies · 256 participants | Very low Downgraded: risk of bias |
Progestogen compared to placebo/no treatment for preventing miscarriage in women with recurrent miscarriage of unclear etiology
Population: women with recurrent miscarriage of unclear etiology
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Miscarriage (all trials) Progestogen vs placebo/no treatment | RR 0.73 [0.54, 1] | 10 studies · 1684 participants | Moderate Downgraded: risk of bias |
Live birth rate Progestogen vs placebo/no treatment | RR 1.07 [1, 1.13] | 6 studies · 1411 participants | Moderate Downgraded: risk of bias |
Preterm birth Progestogen vs placebo/no treatment | RR 1.13 [0.53, 2.41] | 4 studies · 256 participants | Very low Downgraded: risk of bias |