Cochrane · systematic review · CD003281
Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting
Lee, A, Chan, SKC, Fan, LTY · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 25%Very low 2 · 16.7%Low 4 · 33.3%Moderate 3 · 25%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyAcupoint PC6 stimulation versus sham for preventing postoperative nausea and vomiting
Population: People at risk of postoperative nausea and vomiting
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nausea ‐ All trials Acupoint PC6 stimulation vs sham | RR 0.68 [0.6, 0.77] | 40 studies · 4742 participants | Low Downgraded: risk of bias, inconsistency |
Vomiting ‐ All trials Acupoint PC6 stimulation vs sham | RR 0.6 [0.51, 0.71] | 45 studies · 5147 participants | Low Downgraded: risk of bias, inconsistency |
Rescue antiemetics Acupoint PC6 stimulation vs sham | RR 0.64 [0.55, 0.73] | 39 studies · 4622 participants | Low Downgraded: risk of bias, inconsistency |
Adverse effects Acupoint PC6 stimulation vs sham | no estimate extracted | 6 studies · 35 participants | Ungraded |
Acupoint PC6 stimulation versus antiemetic drug for preventing postoperative nausea and vomiting
Population: People at risk of postoperative nausea and vomiting
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nausea ‐ All antiemetics combined Acupoint PC6 stimulation vs antiemetic drug | RR 0.91 [0.75, 1.1] | 14 studies · 1332 participants | Moderate Downgraded: risk of bias |
Vomiting ‐ All antiemetics combined Acupoint PC6 stimulation vs antiemetic drug | RR 0.93 [0.74, 1.17] | 19 studies · 1708 participants | Moderate Downgraded: risk of bias |
Rescue antiemetic Acupoint PC6 stimulation vs antiemetic drug | RR 0.87 [0.65, 1.16] | 9 studies · 895 participants | Moderate Downgraded: risk of bias |
Adverse effects Acupoint PC6 stimulation vs antiemetic drug | no estimate extracted | 4 studies · 11 participants | Ungraded |
Acupoint PC6 stimulation and antiemetic combination compared to antiemetic for preventing postoperative nausea and vomiting
Population: People at risk of postoperative nausea and vomiting
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nausea Acupoint PC6 stimulation and antiemetic combination vs antiemetic | RR 0.79 [0.55, 1.13] | 8 studies · 642 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Vomiting Acupoint PC6 stimulation and antiemetic combination vs antiemetic | RR 0.56 [0.35, 0.91] | 9 studies · 687 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Rescue antiemetic Acupoint PC6 stimulation and antiemetic combination vs antiemetic | RR 0.61 [0.44, 0.86] | 5 studies · 419 participants | Low Downgraded: risk of bias, imprecision |
Adverse effects Acupoint PC6 stimulation and antiemetic combination vs antiemetic | no estimate extracted | 6 studies · 7 participants | Ungraded |
Comparison
Population: patients with a desire to prevent postoperative nausea and vomiting
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nausea ‐ All trials | RR 0.71 [0.61, 0.83] | 27 studies · 2962 participants | Moderate Downgraded: risk of bias, inconsistency |
Vomiting ‐ All trials | RR 0.7 [0.59, 0.83] | 32 studies · 3385 participants | Moderate Downgraded: risk of bias, inconsistency |
Rescue antiemetics | RR 0.69 [0.57, 0.83] | 26 studies · 2661 participants | Moderate Downgraded: risk of bias, inconsistency |
Adverse effects3 | no estimate extracted | NR | No studies |
Comparison
Population: patients with a desire to prevent postoperative nausea and vomiting
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nausea ‐ All antiemetics combined | RR 0.82 [0.6, 1.13] | 9 studies · 660 participants | Moderate Downgraded: risk of bias |
Vomiting ‐ All antiemetics combined | RR 1.01 [0.77, 1.31] | 14 studies · 1036 participants | Moderate Downgraded: risk of bias |
Rescue antiemetic | RR 0.82 [0.59, 1.13] | 7 studies · 527 participants | Moderate Downgraded: risk of bias |
Adverse effects3 | RR 0.47 [0.26, 0.87] | 1 study · 60 participants | Ungraded |