Cochrane · systematic review · CD002798

Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy

Goh, ET, Andersen, ML, Morgan, MY, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Hepato-Biliary2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Flumazenil versus placebo for people with cirrhosis and hepatic encephalopathy

Population: people with hepatic encephalopathy
3 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality
Flumazenil vs placebo
RR 0.75 [0.48, 1.16]11 studies · 842 participantsLow
Downgraded: risk of bias
Hepatic encephalopathy
Flumazenil vs placebo
RR 0.75 [0.71, 0.8]9 studies · 824 participantsLow
Downgraded: risk of bias
Serious adverse events
Flumazenil vs placebo
no estimate extracted11 studies · 842 participantsLow
Downgraded: risk of bias