Cochrane · systematic review · CD001401
Airway clearance techniques compared to no airway clearance techniques for cystic fibrosis
Warnock, L, Gates, A · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Cystic Fibrosis and Genetic DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 1 · 14.3%Very low 2 · 28.6%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings for airway clearance techniques compared with no airway clearance techniques for cystic fibrosis
Population: children and adults with cystic fibrosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lung function: FEV1 % predicted change from baseline Summary of findings for airway clearance techniques vs no airway clearance techniques | no estimate extracted | 1 participants | Ungraded |
Lung function: LCI Summary of findings for airway clearance techniques vs no airway clearance techniques | no estimate extracted | 2 studies · 58 participants | Low Downgraded: imprecision |
Exacerbation rate (number of exacerbations/year) Summary of findings for airway clearance techniques vs no airway clearance techniques | no estimate extracted | NR | No studies |
Mucus transport rate (radio tracer clearance) Summary of findings for airway clearance techniques vs no airway clearance techniques | no estimate extracted | 6 studies · 55 participants | Very low Downgraded: risk of bias, imprecision |
Expectorated secretions (sputum wet weight) Summary of findings for airway clearance techniques vs no airway clearance techniques | no estimate extracted | 5 studies · 47 participants | Very low Downgraded: risk of bias, imprecision |
Exercise tolerance (MSWT) Summary of findings for airway clearance techniques vs no airway clearance techniques | no estimate extracted | NR | No studies |
Well‐being or QoL Summary of findings for airway clearance techniques vs no airway clearance techniques | no estimate extracted | NR | No studies |