Cochrane · systematic review · CD001392
Prolonged antibiotics for non‐cystic fibrosis bronchiectasis in children and adults
Hnin, K, Nguyen, C, Carson‐Chahhoud, KV, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 3 · 75%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Prolonged antibiotics for purulent bronchiectasis in children and adults
Population: adults and children with purulent bronchiectasis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Exacerbations Number of events | OR 0.31 [0.12, 0.52] | 10 studies · 654 participants | Moderate Downgraded: inconsistency |
Hospitalisations Number of events | OR 0.4 [0.14, 1.11] | 7 studies · 643 participants | Moderate Downgraded: inconsistency |
Emergence of resistance Number of events | OR 3.48 [1.2, 10.07] | 6 studies · 431 participants | Moderate Downgraded: imprecision |
St George Respiratory Questionnaire (SGRQ) total Mean and standard deviation. Scale from 0 to 100 | no estimate extracted | 5 studies · 315 participants | Low Downgraded: inconsistency |