Cochrane · systematic review · CD001390
Pneumococcal vaccines for preventing pneumonia in chronic obstructive pulmonary disease
Walters, JAE, Tang, JNQ, Poole, P, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 5 · 71.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pneumoccocal vaccination to prevent pneumonia in chronic obstructive pulmonary disease?
Population: patients with COPD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pneumonia, community acquired, at least 1 episode | OR 0.59 [0.41, 0.85] | 6 studies · 1372 participants | Moderate Downgraded: risk of bias |
Pneumococcal pneumonia, at least 1 episode | OR 0.26 [0.05, 1.31] | 3 studies · 1158 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Death from cardiorespiratory causes | OR 1.07 [0.69, 1.66] | 3 studies · 888 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Death from all causes | OR 1 [0.72, 1.4] | 5 studies · 1053 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Hospital admission: any cause, at least 1 episode | OR 0.74 [0.32, 1.74] | 3 studies · 391 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
COPD exacerbation: at least 1 episode | OR 0.6 [0.39, 0.93] | 4 studies · 446 participants | Moderate Downgraded: risk of bias |
Lung function: FEV1 (L) | no estimate extracted | 1 study · 142 participants | Low Downgraded: risk of bias, imprecision, inconsistency |