Cochrane · systematic review · CD000998
Nutritional supplementation for stable chronic obstructive pulmonary disease
Ferreira, IM, Brooks, D, White, J, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
29
current version
GRADE rated
29
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 24 · 82.8%Moderate 5 · 17.2%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Nutritional supplementation for stable chronic obstructive pulmonary disease (end of intervention)
Population: patients with stable chronic obstructive pulmonary disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Weight (mixed population) kg | no estimate extracted | 14 studies · 512 participants | Moderate Downgraded: risk of bias |
Weight (undernourished) kg | no estimate extracted | 11 studies · 325 participants | Moderate Downgraded: risk of bias |
Fat‐free mass index (mixed population) kg/m2 | no estimate extracted | 3 studies · 93 participants | Low Downgraded: risk of bias, imprecision |
Fat‐free mass index (undernourished patients) kg/m2 | no estimate extracted | 2 studies · 62 participants | Low Downgraded: risk of bias, imprecision |
Mid‐arm muscle circumference (mixed population) cm | no estimate extracted | 9 studies · 246 participants | Low Downgraded: risk of bias, imprecision |
Nutritional supplementation for stable chronic obstructive pulmonary disease (end of intervention)
Population: stable chronic obstructive pulmonary disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Skinfold thickness (mixed measures and mixed population) cm | no estimate extracted | 7 studies · 179 participants | Low Downgraded: risk of bias, imprecision |
Functional exercise capacity ‐ 6‐minute walk test (mixed population) metres | no estimate extracted | 5 studies · 142 participants | Low Downgraded: risk of bias, imprecision |
FEV1 litres and % predicted | no estimate extracted | 7 studies · 228 participants | Low Downgraded: risk of bias, imprecision |
FEV1 litres | no estimate extracted | 2 studies · 76 participants | Low Downgraded: risk of bias, imprecision |
FEV1 % predicted | no estimate extracted | 5 studies · 152 participants | Low Downgraded: risk of bias, imprecision |
MIP (mixed population) cm H2O | no estimate extracted | 9 studies · 245 participants | Low Downgraded: risk of bias, imprecision |
MIP ‐ undernourished cm H2O | no estimate extracted | 7 studies · 189 participants | Low Downgraded: risk of bias, imprecision |
Nutritional supplementation for stable chronic obstructive pulmonary disease (end of intervention)
Population: stable chronic obstructive pulmonary disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
HRQoL (mixed population) CRQ and SGRQ | no estimate extracted | 4 studies · 130 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ SGRQ ‐ subgrouped by domain ‐ total | no estimate extracted | 2 studies · 67 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ SGRQ subgrouped by domain ‐ activity | no estimate extracted | 2 studies · 67 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ SGRQ subgrouped by domain ‐ impact | no estimate extracted | 2 studies · 67 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ SGRQ subgrouped by domain ‐ symptoms | no estimate extracted | 2 studies · 67 participants | Low Downgraded: risk of bias, imprecision |
Nutritional supplementation for stable chronic obstructive pulmonary disease (change from baseline)
Population: patients with stable chronic obstructive pulmonary disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Weight (change from baseline ‐ mixed population) kg | no estimate extracted | 14 studies · 511 participants | Moderate Downgraded: risk of bias |
Weight (change from baseline ‐ undernourished) kg | no estimate extracted | 11 studies · 324 participants | Moderate Downgraded: risk of bias |
Fat‐free mass/fat‐free mass index (change from baseline; mixed population) kg/m2 | no estimate extracted | 5 studies · 287 participants | Low Downgraded: risk of bias, imprecision |
Fat‐free mass/fat‐free mass index (change from baseline; undernourished participants) kg/m2 | no estimate extracted | 3 studies · 125 participants | Low Downgraded: risk of bias, imprecision |
Fat mass/fat mass index (change from baseline; undernourished participants) kg/m2 | no estimate extracted | 2 studies · 91 participants | Moderate Downgraded: imprecision |
Skinfold measures (change from baseline, mixed population) ‐ Triceps skin folds cm | no estimate extracted | 6 studies · 125 participants | Low Downgraded: risk of bias, imprecision |
Nutritional supplementation for stable chronic obstructive pulmonary disease (change from baseline)
Population: patients with stable chronic obstructive pulmonary disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Functional exercise capacity (change from baseline; mixed population) ‐ 6‐minute walk test metres | no estimate extracted | 5 studies · 140 participants | Low Downgraded: risk of bias, imprecision |
MAMC ‐ change from baseline | no estimate extracted | 9 studies · 246 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ CRQ subgrouped by domain (change from baseline; mixed population) ‐ dyspnoea | no estimate extracted | 3 studies · 123 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ CRQ subgrouped by domain (change from baseline; mixed population) ‐ fatigue | no estimate extracted | 3 studies · 123 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ CRQ subgrouped by domain (change from baseline; mixed population) ‐ emotion | no estimate extracted | 3 studies · 123 participants | Low Downgraded: risk of bias, imprecision |
HRQoL ‐ CRQ subgrouped by domain (change from baseline; mixed population) ‐ mastery | no estimate extracted | 3 studies · 123 participants | Low Downgraded: risk of bias, imprecision |