Cochrane · systematic review · CD000990

Exercise for intermittent claudication

Lane, R, Harwood, A, Watson, L, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 4 · 57.1%High 2 · 28.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Is exercise an effective intervention in intermittent claudication?

Population: adults with intermittent claudication
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain‐free walking distance (m)
no estimate extracted9 studies · 391 participantsHigh
Maximum walking distance (m)
no estimate extracted10 studies · 500 participantsHigh
Ankle brachial index
no estimate extracted13 studies · 570 participantsModerate
Downgraded: inconsistency
Mortality: all‐cause deaths
RR 0.92 [0.39, 2.17]5 studies · 540 participantsModerate
Downgraded: imprecision
Amputation
RR 0.2 [0.01, 4.15]1 study · 177 participantsLow
Downgraded: imprecision
Quality of Life SF‐36 Physical Summary score (scale 0 to 100, higher score indicates better quality of life)
no estimate extracted5 studies · 429 participantsModerate
Downgraded: inconsistency
Quality of Life SF‐36 Mental Summary score (scale 0 to 100, higher score indicates better quality of life)
no estimate extracted4 studies · 343 participantsModerate
Downgraded: inconsistency