Cochrane · systematic review · CD000490

Antibiotics for asymptomatic bacteriuria in pregnancy

Smaill, FM, Vazquez, JC · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Pregnancy and Childbirth2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Antibiotics compared to no treatment for asymptomatic bacteriuria in pregnancy

Population: pregnant women with asymptomatic bacteriuria
CD000490.PUB4 (current) · 3 questions
OutcomeEffectEvidenceStatus / GRADE
Development of pyelonephritis
Antibiotics vs no treatment
RR 0.24 [0.13, 0.41]12 studies · 2017 participantsLow
Downgraded: risk of bias, inconsistency
Preterm birth < 37 weeks
Antibiotics vs no treatment
RR 0.34 [0.13, 0.88]3 studies · 327 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Birthweight < 2500 g
Antibiotics vs no treatment
RR 0.64 [0.45, 0.93]6 studies · 1437 participantsLow
Downgraded: risk of bias, imprecision, indirectness

Antibiotic treatment versus no treatment for asymptomatic bacteriuria in pregnancy

Population: Patients with asymptomatic bacteriuria in pregnancy
CD000490.PUB3 · 3 questions
OutcomeEffectEvidenceStatus / GRADE
Development of pyelonephritis
Antibiotic treatment vs no treatment
RR 0.23 [0.13, 0.41]11 studies · 1932 participantsVery low
Downgraded: risk of bias, inconsistency
Preterm birth < 37 weeks
Antibiotic treatment vs no treatment
RR 0.27 [0.11, 0.62]2 studies · 242 participantsLow
Downgraded: risk of bias, imprecision
Birthweight < 2500 g
Antibiotic treatment vs no treatment
RR 0.64 [0.45, 0.93]6 studies · 1437 participantsLow
Downgraded: risk of bias