Cochrane · systematic review · CD000206
Calcium channel blockers for antipsychotic‐induced tardive dyskinesia
Essali, A, Soares‐Weiser, K, Bergman, H, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
4
Included studies
NR
No studies 4 · 57.1%Ungraded 0 · 0%Very low 3 · 42.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyCalcium channel blocking drugs for people with antipsychotic‐induced tardive dyskinesia
Population: people with antipsychotic‐induced tardive dyskinesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Tardive dyskinesia ‐ not improved to a clinically important extent | no estimate extracted | 2 studies · 37 participants | Very low Downgraded: risk of bias, imprecision |
Tardive dyskinesia ‐ deterioration | no estimate extracted | NR | No studies |
Adverse effects ‐ any important adverse effects | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adverse effects ‐ important extrapyramidal adverse effects | no estimate extracted | NR | No studies |
Mental state ‐ deterioration | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Acceptability of treatment ‐ leaving the study early | no estimate extracted | NR | No studies |
Social confidence, social inclusion, social networks or personalised quality of life measures ‐ no clinically significant change | no estimate extracted | NR | No studies |
Calcium channel blocking drugs for people with neuroleptic‐induced tardive dyskinesia
Population: People with neuroleptic‐induced tardive dyskinesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Tardive dyskinesia ‐ any clinically important improvement | no estimate extracted | 0 studies · 0 participants | Ungraded |
Tardive dyskinesia ‐ any improvement | no estimate extracted | 0 studies · 0 participants | Ungraded |
Acceptability of the treatment to the participant group | no estimate extracted | 0 studies · 0 participants | Ungraded |
Quality of life / satisfaction with care | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects ‐ important extrapyramidal adverse effects | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects ‐ any important adverse effects | no estimate extracted | 0 studies · 0 participants | Ungraded |
Hospital admission | no estimate extracted | 0 studies · 0 participants | Ungraded |