Cochrane · systematic review · CD000088

Family intervention for schizophrenia

Pharoah, F, Mari, JJ, Rathbone, J, et al. · Cochrane Database of Systematic Reviews · 2010 · Cochrane Library

Schizophrenia2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 16.7%Low 5 · 83.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

ANY FAMILY BASED INTERVENTIONS (>5 sessions) compared to STANDARD CARE for schizophrenia

Population: patients with schizophrenia
CD000088.PUB3 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Service utilisation: Hospital admission ‐ at about 12 months
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.78 [0.63, 0.98]9 studies · 532 participantsLow
Downgraded: publication bias
Global state: Relapse ‐ at about 12 months
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.55 [0.48, 0.62]32 studies · 2981 participantsLow
Downgraded: publication bias
Compliance: Poor compliance with medication
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.6 [0.49, 0.73]10 studies · 695 participantsLow
Downgraded: publication bias
Social functioning: Specific ‐ unemployed ‐ at about 1 year
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 1.06 [0.89, 1.25]5 studies · 285 participantsLow
Downgraded: publication bias
Social functioning: Specific ‐ unable to live independently ‐ at about 1 year
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.83 [0.66, 1.03]3 studies · 164 participantsLow
Downgraded: publication bias
Family outcome: Burden ‐ not improved/worse (objective burden related to self‐sufficiency)
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.53 [0.21, 1.37]1 study · 51 participantsVery low
Downgraded: publication bias

ANY FAMILY BASED INTERVENTIONS (>5 sessions) compared to STANDARD CARE for schizophrenia

Population: patients with schizophrenia
CD000088.PUB2 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Service utilisation: Hospital admission ‐ at about 12 months
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.78 [0.63, 0.98]9 studies · 532 participantsLow
Downgraded: publication bias
Global state: Relapse ‐ at about 12 months
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.55 [0.48, 0.62]32 studies · 2981 participantsLow
Downgraded: publication bias
Compliance: Poor compliance with medication
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.6 [0.49, 0.73]10 studies · 695 participantsLow
Downgraded: publication bias
Social functioning: Specific ‐ unemployed ‐ at about 1 year
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 1.06 [0.89, 1.25]5 studies · 285 participantsLow
Downgraded: publication bias
Social functioning: Specific ‐ unable to live independently ‐ at about 1 year
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.83 [0.66, 1.03]3 studies · 164 participantsLow
Downgraded: publication bias
Family outcome: Burden ‐ not improved/worse (objective burden related to self‐sufficiency)
ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs STANDARD CARE
RR 0.53 [0.21, 1.37]1 study · 51 participantsVery low
Downgraded: publication bias