Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 2 · 28.6%High 1 · 14.3%

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Fever · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) showed no clear difference in fever compared with control (moderate certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.98 [0.84, 1.13]
3 studies · 132261 participants
Moderate

Erythema · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) showed no clear difference in erythema compared with control (low certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 1.15 [0.33, 4.03]
3 studies · 132261 participants
Low

Incidence of typhoid fever – year 1 Blood culture · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) leads to lower incidence of typhoid fever – year 1 Blood culture compared with control (high certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.31 [0.26, 0.37]
3 studies · 99797 participants
High

Incidence of typhoid fever – year 2 · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) probably leads to lower incidence of typhoid fever – year 2 compared with control (moderate certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.41 [0.31, 0.55]
4 studies · 194969 participants
Moderate

Cases of typhoid fever, Year 3 · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) may leads to lower incidence of typhoid fever –year 3 compared with control (low certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.5 [0.32, 0.78]
1 study · 11384 participants
Low

Cumulative cases of typhoid fever at 2.5 to 3 years · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) may leads to lower cumulative cases of typhoid fever at 2.5 to 3 years compared with control (low certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.45 [0.3, 0.7]
1 study · 11384 participants
Low

Serious adverse events · adults and children of 2 years of age and older

The review found no eligible studies for this question.

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found