Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

30 questions · 30 findings · 1 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 5 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 3.3%Moderate 7 · 23.3%High 17 · 56.7%

Intervention not reported

AIS associated with HPV16/18 or 6/11/16/18 (age 15 to 26 years) · adolescent girls and women aged 15 to 45 years who were HPV16/18 negative before vaccination

The intervention probably leads to lower AIS associated with HPV16/18 or 6/11/16/18 (age 15 to 26 years) (moderate certainty).

1 finding from 1 review

Intervention not reported

Any CIN2+ irrespective of HPV type, bivalent or quadrivalent vaccine · adolescent girls and women aged 15 to 26 years who are hrHPV negative before vaccination

The intervention leads to lower any CIN2+ irrespective of HPV type, bivalent or quadrivalent vaccine (high certainty).

1 finding from 1 review

Intervention not reported

Any CIN3+ irrespective of HPV type, bivalent or quadrivalent vaccine · adolescent girls and women aged 15 to 26 years who are hrHPV negative before vaccination

The intervention showed no clear difference in any CIN3+ irrespective of HPV type, bivalent or quadrivalent vaccine (moderate certainty).

1 finding from 1 review