Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Restored patency · patients with occluded central venous catheter

Urokinase (any strength) may leads to higher restored patency compared with placebo (low certainty).

1 finding from 1 review

Interventions for restoring patency of occluded central venous catheter lumens 2012 · Cochrane Headline outcomes only
RR 2.09 [1.47, 2.95]
2 studies · 287 participants
Low

Adverse effects · patients with occluded central venous catheter

It is very uncertain whether urokinase (any strength) changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Interventions for restoring patency of occluded central venous catheter lumens 2012 · Cochrane Headline outcomes only
RR 2.88 [0.38, 21.93]
1 study · 72 participants
Very low