Findings

What do systematic reviews say?

11 questions · 11 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 36.4%Low 1 · 9.1%Moderate 6 · 54.5%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Two weeks of 5FC + FLU vs two weeks of AmBd + FLU · Mortality: 10 weeks
  Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
  RR 0.85 [0.64, 1.13]
  1 study · 339 participants
  Moderate
Direct match · question page
- Two weeks of 5FC + FLU vs two weeks of AmBd + 5FC · Mortality: 10 weeks
  Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
  RR 0.92 [0.69, 1.23]
  1 study · 340 participants
  Moderate
Related · question page
- Two weeks of FLU vs two weeks of 5FC + FLU · Mortality: 10 weeks
  Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
  RR 1.46 [0.96, 2.23]
  2 studies · 98 participants
  Very low
Related · question page
- One week of AmBd + FLU vs two weeks of 5FC + FLU · Mortality: 10 weeks
  Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
  RR 1.39 [1.07, 1.8]
  1 study · 336 participants
  Moderate
Related · question page
- One week of AmBd + 5FC vs two weeks of 5FC + FLU · Mortality: 10 weeks
  Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
  RR 0.68 [0.47, 0.99]
  1 study · 338 participants
  Moderate

Two weeks of 5FC + FLU vs two weeks of AmBd + 5FC

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

Two weeks of 5FC + FLU showed no clear difference in mortality: 10 weeks compared with two weeks of AmBd + 5FC (moderate certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 0.92 [0.69, 1.23]
1 study · 340 participants
Moderate

Two weeks of 5FC + FLU vs two weeks of AmBd + FLU

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

Two weeks of 5FC + FLU showed no clear difference in mortality: 10 weeks compared with two weeks of AmBd + FLU (moderate certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 0.85 [0.64, 1.13]
1 study · 339 participants
Moderate

Two weeks of AmBd + 5FC + FLU vs two weeks of AmBd + 5FC

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

It is very uncertain whether two weeks of AmBd + 5FC + FLU changes mortality: 10 weeks compared with two weeks of AmBd + 5FC (very low certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 2.81 [0.33, 24.16]
1 study · 31 participants
Very low

Two weeks of AmBd + 5FC + FLU vs two weeks of AmBd + FLU

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

It is very uncertain whether two weeks of AmBd + 5FC + FLU changes mortality: 10 weeks compared with two weeks of AmBd + FLU (very low certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 0.43 [0.13, 1.37]
1 study · 32 participants
Very low

Two weeks of FLU vs two weeks of 5FC + FLU

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

It is very uncertain whether two weeks of FLU changes mortality: 10 weeks compared with two weeks of 5FC + FLU (very low certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 1.46 [0.96, 2.23]
2 studies · 98 participants
Very low

Two weeks of AmBd + 5FC + FLU vs two weeks of AmBd

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

It is very uncertain whether two weeks of AmBd + 5FC + FLU changes mortality: 10 weeks compared with two weeks of AmBd (very low certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 1 [0.24, 4.23]
1 study · 32 participants
Very low

Two weeks of AmBd + 5FC vs two weeks of AmBd + FLU

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

Two weeks of AmBd + 5FC showed no clear difference in mortality: 10 weeks compared with two weeks of AmBd + FLU (low certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 0.9 [0.69, 1.19]
4 studies · 538 participants
Low

One week of AmBd + FLU vs two weeks of 5FC + FLU

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

One week of AmBd + FLU probably leads to higher mortality: 10 weeks compared with two weeks of 5FC + FLU (moderate certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 1.39 [1.07, 1.8]
1 study · 336 participants
Moderate

One week of AmBd + 5FC vs two weeks of 5FC + FLU

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

One week of AmBd + 5FC probably leads to lower mortality: 10 weeks compared with two weeks of 5FC + FLU (moderate certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 0.68 [0.47, 0.99]
1 study · 338 participants
Moderate

One week of AmBd + FLU vs two weeks of AmBd + 5FC

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

One week of AmBd + FLU showed no clear difference in mortality: 10 weeks compared with two weeks of AmBd + 5FC (moderate certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 1.27 [0.94, 1.72]
1 study · 226 participants
Moderate

One week of AmBd + 5FC vs two weeks of AmBd + FLU

Mortality: 10 weeks · HIV‐infected individual with first episode of cryptococcal meningitis

One week of AmBd + 5FC probably leads to lower mortality: 10 weeks compared with two weeks of AmBd + FLU (moderate certainty).

1 finding from 1 review

Treatment for HIV‐associated cryptococcal meningitis 2018 · Cochrane Headline outcomes only
RR 0.58 [0.39, 0.86]
1 study · 227 participants
Moderate