Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews

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No studies found 5 · 62.5%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 1 · 12.5%Moderate 1 · 12.5%High 0 · 0%

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Antibody response (geometric mean titre) · 9‐ to 14‐year‐old females and males

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 16 participants
Moderate

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Invasive cervical, vaginal, vulval, anal, or penile cancer · 9‐ to 14‐year‐old females and males

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

High‐grade cervical, vulval, vaginal, penile, or anal intraepithelial neoplasia · 9‐ to 14‐year‐old females and males

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Overall local/injection site adverse events · 9‐ to 14‐year‐old females and males

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Overall systemic events and general symptoms · 9‐ to 14‐year‐old females and males

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Serious adverse events at up to 5‐year · 9‐ to 14‐year‐old females and males

It is very uncertain whether two doses of HPV vaccine with longer interval changes serious adverse events at up to 5‐year compared with two doses of HPV vaccine with shorter interval (very low certainty).

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
OR 1.15 [0.55, 2.41]
1 study · 481 participants
Very low

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Mortality at up to 5‐year · 9‐ to 14‐year‐old females and males

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 481 participants
Low

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Clinical and harms outcomes* · 9‐ to 14‐year‐old females and males

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found