Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Transdermal beta‐estradiol patch vs placebo

Hot flush frequency (number/day) · women with hot flushes

Transdermal beta‐estradiol patch showed no clear difference in frequency of hot flushes Beta‐estradiol patch 0.0375‐0.10 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 793 participants
Low

Transdermal beta‐estradiol patch vs conjugated equine estrogens

Hot flush frequency (number/day) · women with hot flushes

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 711 participants
Low

Transdermal beta‐estradiol patch vs conjugated equine estrogens

Adverse events Beta‐estradiol patch 0.05 or 0.1 mg/day vs CEE 0.625 or 1.25 mg/day · women with hot flushes

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 711 participants
Very low

Transdermal beta‐estradiol patch vs placebo

Intensity of hot flushes Beta‐estradiol patch 0.025‐0.05 mg/day · women with hot flushes

Transdermal beta‐estradiol patch showed no clear difference in intensity of hot flushes Beta‐estradiol patch 0.025‐0.05 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 393 participants
Low

Transdermal beta‐estradiol patch vs placebo

Adverse effects Beta‐estradiol patch dose 0.10 mg/day · women with hot flushes

Transdermal beta‐estradiol patch may leads to higher adverse effects Beta‐estradiol patch dose 0.10 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
OR 2.14 [1.29, 3.54]
9 studies · 1822 participants
Low