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Evidence found and GRADE certainty

21 questions · 23 findings · 2 reviews · Wounds

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No studies found 5 · 21.7%GRADE not reported 0 · 0%Very low 10 · 43.5%Low 6 · 26.1%Moderate 2 · 8.7%High 0 · 0%

Silver‐based antiseptics vs topical antibiotics

Time to complete healing · people with burns

Silver‐based antiseptics showed no clear difference in wound healing: time to complete healing (time‐to‐event data) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    HR 1.25 [0.94, 1.67]
    3 studies · 259 participants
    Low

Silver‐based antiseptics vs topical antibiotics

Wound healing · people with burns

Silver‐based antiseptics showed no clear difference in wound healing (mean time to healing) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    10 studies · 1085 participants
    Low

Silver‐based antiseptics vs topical antibiotics

Number of wounds healed · people with burns

Silver‐based antiseptics showed no clear difference in wound healing (number of healing events) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 1.17 [1, 1.37]
    5 studies · 408 participants
    Low

Topical antibiotics vs antiseptic agent

Allergic contact dermatitis · people presenting for surgery where healing of surgical wound planned to be by primary intention

It is very uncertain whether topical antibiotics changes allergic contact dermatitis compared with antiseptic (very low certainty).

1 finding from 1 review

Honey vs topical antibiotics

Peristent infection: honey versus SSD · people with burns

It is very uncertain whether honey changes peristent infection: honey versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.1 [0.05, 0.19]
    2 studies · 170 participants
    Very low

Honey vs topical antibiotics

Adverse events: honey versus SSD · people with burns

It is very uncertain whether honey changes adverse events: honey versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.2 [0.01, 3.97]
    3 studies · 250 participants
    Very low

Aloe vera vs topical antibiotics

Wound healing · people with burns

Aloe vera showed no clear difference in wound healing (number of healing events): Aloe Vera versus SSD compared with topical antibiotics (low certainty).

2 findings from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 1.41 [0.7, 2.85]
    1 study · 38 participants
    Low
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    3 studies · 210 participants
    Very low

Aloe vera vs topical antibiotics

Infection: Aloe Vera versus SSD · people with burns

It is very uncertain whether aloe vera changes infection: Aloe Vera versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.93 [0.26, 3.34]
    3 studies · 221 participants
    Very low

Iodine vs topical antibiotics

Wound healing · people with burns

It is very uncertain whether iodine changes wound healing (mean time to healing) compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    2 studies · 148 participants
    Very low

Iodine vs topical antibiotics

Infection · people with burns

The review found no eligible studies for this question.

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Iodine vs topical antibiotics

Adverse events · people with burns

It is very uncertain whether iodine changes adverse events compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.86 [0.35, 2.1]
    1 study · 40 participants
    Very low

Honey vs topical antibiotics

Time to complete healing · people with burns

Honey probably leads to higher wound healing: time to complete healing (time‐to‐event data): honey… compared with topical antibiotics (moderate certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    HR 2.45 [1.71, 3.52]
    5 studies · 580 participants
    Moderate

Honey vs topical antibiotics

Wound healing · people with burns

It is very uncertain whether honey changes wound healing (mean time to healing): honey versus SSD compared with topical antibiotics (very low certainty).

2 findings from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    6 studies · 712 participants
    Very low
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 2.18 [1.15, 4.13]
    4 studies · 318 participants
    Low