Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Neonatal

Sort:Best matchNewest Highest certainty Download CSV

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 5 · 71.4%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Topical anesthetics vs placebo or no intervention

Successful LP on first attempt № of LPs: 100(1 quasi‐RCT) · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

Total number of LP attempts № of LPs: 100(1 quasi‐RCT) · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

Episodes of bradycardia · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

NFCS pain score during the procedure№ of infants: 112(2 RCTs) Score · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Topical anesthetics vs placebo or no intervention

Episodes of desaturation, defined as a decrease of SpO2 to less than 80%, with no minimum duration specified—not reported · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

Apnea: number of episodesduring the procedure · lumbar puncture in newborn infants

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical anesthetics vs placebo or no intervention

Episodes of apnea · lumbar puncture in newborn infants

It is very uncertain whether topical anesthetics changes apnea: occurrence of one or more episodes№ of LPs: 100(1 quasi‐RCT) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
RR 3.24 [0.14, 77.79]
Studies not reported
Very low