Findings

What do systematic reviews say?

4 questions · 10 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 10 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Fluoride-containing dental care products (mainly fluoride toothpaste) vs Dietary fluoride sources (drinking water, beverages, food)

Contribution of dental care products to total daily fluoride intake (TDFI), by tap-water fluoride level · Children using fluoride-containing dental care products (majority of included studies)

In children in low-fluoridated tap water areas, dental care products contributed on average 39% of total fluoride exposure (ungraded).

5 findings from 1 review

Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · Low-fluoridated tap water (0.3-0.51 mg/L)
Mean contribution to TDFI (%) 39
7 studies
GRADE not reported
Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · High-fluoridated tap water (0.78-1.5 mg/L)
Mean contribution to TDFI (%) 41
8 studies
GRADE not reported
Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · Medium-fluoridated tap water (0.52-0.77 mg/L)
Mean contribution to TDFI (%) 51
14 studies
GRADE not reported

Show 2 more findings

Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · Extreme-fluoridated tap water (>1.5 mg/L)
Mean contribution to TDFI (%) 3
2 studies
GRADE not reported
Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · Poor-fluoridated tap water (<0.3 mg/L)
Mean contribution to TDFI (%) 45
10 studies
GRADE not reported

Fluoride-containing dental care products (mainly fluoride toothpaste) vs Dietary fluoride sources (drinking water, beverages, food)

Contribution of dental care products to total daily fluoride intake (TDFI), by tap-water fluoride level · Adults using fluoride-containing dental care products (two included studies [28,47]; aged 20-35)

In adults in poor-fluoridated tap water areas, dental care products contributed on average 12% of total fluoride exposure (ungraded; 1-2 studies).

3 findings from 1 review

Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · Poor-fluoridated tap water (<0.3 mg/L)
Mean contribution to TDFI (%) 12
1 study
GRADE not reported
Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · Medium-fluoridated tap water (0.52-0.77 mg/L)
Mean contribution to TDFI (%) 53
1 study
GRADE not reported
Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · Low-fluoridated tap water (0.3-0.51 mg/L)
Mean contribution to TDFI (%) 95
1 study
GRADE not reported

Fluoride-containing dental care products (mainly fluoride toothpaste; one study also included fluoride varnish) vs Dietary fluoride sources (drinking water, beverages, food)

Contribution of dental care products to total daily fluoride intake (TDFI) · Humans using fluoride-containing dental care products; 28 included studies, mostly young children, only two studies in adults (aged…

Fluoride-containing dental care products (mainly toothpaste) contributed on average 38% (SD 27%) of total daily fluoride intake, regardless of tap-water fluoride level or age (ungraded; descriptive synthesis, no meta-analysis).

1 finding from 1 review

Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Habitual daily intake · Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings
Mean contribution to TDFI (%) 38
28 studies
GRADE not reported

Daily fluoride intake from toothpaste vs Child age (across age groups)

Association between age and daily fluoride intake from toothpaste · Children using fluoride toothpaste (all tap-water fluoride categories)

There was no correlation between daily fluoride intake from toothpaste and the age of children (all R2 < 0.14), across all tap-water fluoride categories (ungraded).

1 finding from 1 review

Fluoride Intake Through Dental Care Products: A Systematic Review. 2022 All outcomes
Multiple countries (28 studies; ~43% conducted in Brazil); community/general-population settings · All tap-water fluoride categories; Levy et al. [20,22,24] data excluded
R2 (coefficient of determination) <0.14
Studies not reported
GRADE not reported