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Evidence found and GRADE certainty

12 questions · 13 findings · 2 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 1 · 7.7%Very low 2 · 15.4%Low 3 · 23.1%Moderate 7 · 53.8%High 0 · 0%

Antioestrogen vs antioestrogen

Clinical pregnancy rate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether antioestrogen changes clomiphene citrate plus tamoxifen versus clomiphene citrate ‐… compared with antioestrogen (very low certainty).

2 findings from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Endometrial Polyps · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance probably leads to lower endometrial polyps compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Endometrial Hyperplasia · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance probably leads to lower endometrial hyperplasia compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Fibroids · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance showed no clear difference in fibroids compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Abnormal Vaginal Bleeding or Spotting · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance probably leads to higher abnormal vaginal bleeding or spotting compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Breast cancer recurrence · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance showed no clear difference in breast cancer recurrence compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Breast Cancer‐related Death · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance showed no clear difference in breast cancer‐related death compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review