Postoperative pain intensity in the immediate postobturation period (up to 72 hours), continuous (VAS) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in postoperative pain intensity in the immediate postobturation period… compared with multiple-visit root canal treatment (two or more visits) (low certainty).
1 finding from 1 review
Patient-reported pain intensity (sum of pain intensity difference (SPID) and sum of pain percussion intensity difference (SPPID)) · Adults over 18 years presenting with a single tooth with a clinical diagnosis of irreversible pulpitis
1 finding from 1 review
Corresponding risk (Antibiotics): The in between-group differences (median +/- IQR) in SPID for the penicillin group were 6.0 +/- 10.5, and for placebo 6.0 +/- 9.5. The SPPID for the penicillin group was 3.5 +/- 7.5…
1 study · 40 participants
Low
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Glutaraldehyde + zinc oxide and eugenol (ZOE) showed no clear difference in clinical failure compared with full strength formocresol (FC); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with endoflas chlorophenol free (Endoflas-CF); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Low-level laser therapy (LLLT) + calcium hydroxide showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Biodentine showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) probably leads to higher radiological failure compared with formocresol (FC) (moderate certainty).
2 findings from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Mineral trioxide aggregate (MTA) may leads to lower radiological failure compared with calcium hydroxide (CH) (low certainty).
2 findings from 1 review
RR 0.12 [0.04, 0.36]
4 studies · 150 participants
Low
No radiological failure in any participant; not estimable
1 study · 50 participants
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Ferric sulphate/MTA pulpotomy showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE) pulpectomy; GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether diode laser changes clinical failure compared with electrosurgery (very low certainty).
1 finding from 1 review
Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Mineral trioxide aggregate (MTA)
Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Assessed pain, soft tissue pathology, mobility, radiolucency, root resorption, pulp canal obliteration (Doyle 2010); no clinical/radiological failure outcome; no significant differences
1 study · 130 participants
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Ferric sulphate (FS) showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with glutaraldehyde + zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in clinical failure compared with full strength formocresol (FC); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether mineral trioxide aggregate (MTA) changes clinical failure compared with 3Mixtatin (very low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review