Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

219 questions · 225 findings · 3 reviews · Dental caries

No studies found 10 · 4.4%GRADE not reported 150 · 66.7%Very low 32 · 14.2%Low 24 · 10.7%Moderate 9 · 4%High 0 · 0%

Intensity modulated radiotherapy (IMRT) vs Conventional or other radiotherapy

Outcome not reported · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…

The review found no eligible studies for this question.

1 finding from 1 review

Glutaraldehyde + zinc oxide and eugenol (ZOE) vs Full strength formocresol (FC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + zinc oxide and eugenol (ZOE) showed no clear difference in clinical failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Metapex (calcium hydroxide/iodoform) vs Endoflas chlorophenol free (Endoflas-CF)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with endoflas chlorophenol free (Endoflas-CF); GRADE not reported.

1 finding from 1 review

Calcium hydroxide (CH) vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) probably leads to higher radiological failure compared with formocresol (FC) (moderate certainty).

2 findings from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) may leads to lower radiological failure compared with calcium hydroxide (CH) (low certainty).

2 findings from 1 review

Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Zinc oxide and eugenol (ZOE) pulpectomy

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Ferric sulphate/MTA pulpotomy showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE) pulpectomy; GRADE not reported.

1 finding from 1 review

Diode laser vs electrosurgery

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether diode laser changes clinical failure compared with electrosurgery (very low certainty).

1 finding from 1 review

Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Mineral trioxide aggregate (MTA)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    mean 22 months
    Assessed pain, soft tissue pathology, mobility, radiolucency, root resorption, pulp canal obliteration (Doyle 2010); no clinical/radiological failure outcome; no significant differences
    1 study · 130 participants
    GRADE not reported

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Glutaraldehyde + calcium hydroxide (CH) vs Glutaraldehyde + zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with glutaraldehyde + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review